Coronavirus Disease 2019 (COVID–19): A Short Review on Hematological Manifestations

Infection with severe acute respiratory syndrome coronavirus 2 (SARS–CoV–2) is a rapidly spreading and devastating global pandemic. Many researchers are attempting to clarify the mechanisms of infection and to develop a drug or vaccine against the virus, but there are still no proven effective treat...

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Main Authors: Artur Słomka, Mariusz Kowalewski, Ewa Żekanowska
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Pathogens
Subjects:
Online Access:https://www.mdpi.com/2076-0817/9/6/493
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author Artur Słomka
Mariusz Kowalewski
Ewa Żekanowska
author_facet Artur Słomka
Mariusz Kowalewski
Ewa Żekanowska
author_sort Artur Słomka
collection DOAJ
description Infection with severe acute respiratory syndrome coronavirus 2 (SARS–CoV–2) is a rapidly spreading and devastating global pandemic. Many researchers are attempting to clarify the mechanisms of infection and to develop a drug or vaccine against the virus, but there are still no proven effective treatments. The present article reviews the common presenting hematological manifestations of coronavirus disease 2019 (COVID–19). Elucidating the changes in hematological parameters in SARS–CoV–2 infected patients could help to understand the pathophysiology of the disease and may provide early clues to diagnosis. Several studies have shown that hematological parameters are markers of disease severity and suggest that they mediate disease progression.
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spelling doaj.art-126b2fa93fd940aa8458f9c099fe30c62023-11-20T04:29:40ZengMDPI AGPathogens2076-08172020-06-019649310.3390/pathogens9060493Coronavirus Disease 2019 (COVID–19): A Short Review on Hematological ManifestationsArtur Słomka0Mariusz Kowalewski1Ewa Żekanowska2Department of Pathophysiology, Nicolaus Copernicus University in Toruń, Ludwik Rydygier Collegium Medicum, 85–094 Bydgoszcz, PolandClinical Department of Cardiac Surgery, Central Clinical Hospital of the Ministry of Interior and Administration, Centre of Postgraduate Medical Education, 02–607 Warsaw, PolandDepartment of Pathophysiology, Nicolaus Copernicus University in Toruń, Ludwik Rydygier Collegium Medicum, 85–094 Bydgoszcz, PolandInfection with severe acute respiratory syndrome coronavirus 2 (SARS–CoV–2) is a rapidly spreading and devastating global pandemic. Many researchers are attempting to clarify the mechanisms of infection and to develop a drug or vaccine against the virus, but there are still no proven effective treatments. The present article reviews the common presenting hematological manifestations of coronavirus disease 2019 (COVID–19). Elucidating the changes in hematological parameters in SARS–CoV–2 infected patients could help to understand the pathophysiology of the disease and may provide early clues to diagnosis. Several studies have shown that hematological parameters are markers of disease severity and suggest that they mediate disease progression.https://www.mdpi.com/2076-0817/9/6/493coronavirus disease 2019 COVID–19severe acute respiratory syndrome coronavirus 2 SARS–CoV–2hematologyhemostasiscytokine storm
spellingShingle Artur Słomka
Mariusz Kowalewski
Ewa Żekanowska
Coronavirus Disease 2019 (COVID–19): A Short Review on Hematological Manifestations
Pathogens
coronavirus disease 2019 COVID–19
severe acute respiratory syndrome coronavirus 2 SARS–CoV–2
hematology
hemostasis
cytokine storm
title Coronavirus Disease 2019 (COVID–19): A Short Review on Hematological Manifestations
title_full Coronavirus Disease 2019 (COVID–19): A Short Review on Hematological Manifestations
title_fullStr Coronavirus Disease 2019 (COVID–19): A Short Review on Hematological Manifestations
title_full_unstemmed Coronavirus Disease 2019 (COVID–19): A Short Review on Hematological Manifestations
title_short Coronavirus Disease 2019 (COVID–19): A Short Review on Hematological Manifestations
title_sort coronavirus disease 2019 covid 19 a short review on hematological manifestations
topic coronavirus disease 2019 COVID–19
severe acute respiratory syndrome coronavirus 2 SARS–CoV–2
hematology
hemostasis
cytokine storm
url https://www.mdpi.com/2076-0817/9/6/493
work_keys_str_mv AT artursłomka coronavirusdisease2019covid19ashortreviewonhematologicalmanifestations
AT mariuszkowalewski coronavirusdisease2019covid19ashortreviewonhematologicalmanifestations
AT ewazekanowska coronavirusdisease2019covid19ashortreviewonhematologicalmanifestations