Basosquamous Cell Carcinoma Developing from a Renal Transplantation Recipient
We describe a case of basosquamous cell carcinoma arising from a 52-year-old Japanese renal transplantation recipient (RTR). In the present case, we investigated the immunohistochemical profiles of tumor-infiltrating lymphocytes, focusing on cytotoxic granules, granulysin-bearing cells and immunosup...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Karger Publishers
2012-10-01
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| Series: | Case Reports in Dermatology |
| Subjects: | |
| Online Access: | http://www.karger.com/Article/FullText/345095 |
| _version_ | 1811239505727848448 |
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| author | Akira Tsukada Taku Fujimura Sadanori Furudate Yumi Kambayashi Akira Hashimoto Setsuya Aiba |
| author_facet | Akira Tsukada Taku Fujimura Sadanori Furudate Yumi Kambayashi Akira Hashimoto Setsuya Aiba |
| author_sort | Akira Tsukada |
| collection | DOAJ |
| description | We describe a case of basosquamous cell carcinoma arising from a 52-year-old Japanese renal transplantation recipient (RTR). In the present case, we investigated the immunohistochemical profiles of tumor-infiltrating lymphocytes, focusing on cytotoxic granules, granulysin-bearing cells and immunosuppressive cells, such as regulatory T cells and tumor-associated macrophages. Our present study suggests some of the possible mechanisms for the carcinogenesis of cutaneous malignancy in RTRs. |
| first_indexed | 2024-04-12T13:02:09Z |
| format | Article |
| id | doaj.art-126e0397c5cd44a4a65d584c5a280dea |
| institution | Directory Open Access Journal |
| issn | 1662-6567 |
| language | English |
| last_indexed | 2024-04-12T13:02:09Z |
| publishDate | 2012-10-01 |
| publisher | Karger Publishers |
| record_format | Article |
| series | Case Reports in Dermatology |
| spelling | doaj.art-126e0397c5cd44a4a65d584c5a280dea2022-12-22T03:32:08ZengKarger PublishersCase Reports in Dermatology1662-65672012-10-014322723210.1159/000345095345095Basosquamous Cell Carcinoma Developing from a Renal Transplantation RecipientAkira TsukadaTaku FujimuraSadanori FurudateYumi KambayashiAkira HashimotoSetsuya AibaWe describe a case of basosquamous cell carcinoma arising from a 52-year-old Japanese renal transplantation recipient (RTR). In the present case, we investigated the immunohistochemical profiles of tumor-infiltrating lymphocytes, focusing on cytotoxic granules, granulysin-bearing cells and immunosuppressive cells, such as regulatory T cells and tumor-associated macrophages. Our present study suggests some of the possible mechanisms for the carcinogenesis of cutaneous malignancy in RTRs.http://www.karger.com/Article/FullText/345095Basosquamous cell carcinomaImmunosuppressive cellsCD163+ M2 macrophageCarcinogenesis |
| spellingShingle | Akira Tsukada Taku Fujimura Sadanori Furudate Yumi Kambayashi Akira Hashimoto Setsuya Aiba Basosquamous Cell Carcinoma Developing from a Renal Transplantation Recipient Case Reports in Dermatology Basosquamous cell carcinoma Immunosuppressive cells CD163+ M2 macrophage Carcinogenesis |
| title | Basosquamous Cell Carcinoma Developing from a Renal Transplantation Recipient |
| title_full | Basosquamous Cell Carcinoma Developing from a Renal Transplantation Recipient |
| title_fullStr | Basosquamous Cell Carcinoma Developing from a Renal Transplantation Recipient |
| title_full_unstemmed | Basosquamous Cell Carcinoma Developing from a Renal Transplantation Recipient |
| title_short | Basosquamous Cell Carcinoma Developing from a Renal Transplantation Recipient |
| title_sort | basosquamous cell carcinoma developing from a renal transplantation recipient |
| topic | Basosquamous cell carcinoma Immunosuppressive cells CD163+ M2 macrophage Carcinogenesis |
| url | http://www.karger.com/Article/FullText/345095 |
| work_keys_str_mv | AT akiratsukada basosquamouscellcarcinomadevelopingfromarenaltransplantationrecipient AT takufujimura basosquamouscellcarcinomadevelopingfromarenaltransplantationrecipient AT sadanorifurudate basosquamouscellcarcinomadevelopingfromarenaltransplantationrecipient AT yumikambayashi basosquamouscellcarcinomadevelopingfromarenaltransplantationrecipient AT akirahashimoto basosquamouscellcarcinomadevelopingfromarenaltransplantationrecipient AT setsuyaaiba basosquamouscellcarcinomadevelopingfromarenaltransplantationrecipient |