Association of inferior division MCA stroke location with populations with atrial fibrillation incidence
Background and Aim: Considering the anatomical features of Middle Cerebral Artery (MCA) bifurcation, larger emboli are more likely to enter the inferior division over the superior division. Since emboli of cardiac origin are larger on average than emboli of arterial origin, we hypothesize that the i...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2023-04-01
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| Series: | Heliyon |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405844023024945 |
| _version_ | 1797836928971702272 |
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| author | Ganghyun Kim Emilia Vitti Melissa D. Stockbridge Jeffrey L. Saver Argye E. Hillis Andreia V. Faria |
| author_facet | Ganghyun Kim Emilia Vitti Melissa D. Stockbridge Jeffrey L. Saver Argye E. Hillis Andreia V. Faria |
| author_sort | Ganghyun Kim |
| collection | DOAJ |
| description | Background and Aim: Considering the anatomical features of Middle Cerebral Artery (MCA) bifurcation, larger emboli are more likely to enter the inferior division over the superior division. Since emboli of cardiac origin are larger on average than emboli of arterial origin, we hypothesize that the infarcts in temporal and parietal lobes are more likely associated to atrial fibrillation than those in the frontal lobes, therefore occurring more often in populations with higher incidence of atrial fibrillation, such as male (compared to women) and white (compared to black) patients.Methods: We included 197 patients with MCA “temporoparietal predominant” infarcts and 105 with “frontal predominant” infarcts. Variations between stroke location (frontal or temporoparietal), sex, and race were examined via Chi-square test.Results: Male patients were more likely than female patients to be afflicted by temporoparietal strokes versus frontal strokes, while white patients had greater likelihood than black patients to be afflicted by temporoparietal strokes versus frontal strokes. Patients with confirmed diagnosis of atrial fibrillation display more temporoparietal strokes compared to frontal strokes.Conclusion: Temporoparietal MCA ischemic strokes occur more frequently in male and white patients: populations with known increased incidence of atrial fibrillation. In addition, population-specific anatomical characteristics of the MCA bifurcation might favor the larger cardiac emboli to enter the inferior division and cause temporoparietal infarcts. This association can help guide search for the most likely etiology of infarcts. |
| first_indexed | 2024-04-09T15:16:47Z |
| format | Article |
| id | doaj.art-12710248a6ee42a48cc9329c686ae6cb |
| institution | Directory Open Access Journal |
| issn | 2405-8440 |
| language | English |
| last_indexed | 2024-04-09T15:16:47Z |
| publishDate | 2023-04-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Heliyon |
| spelling | doaj.art-12710248a6ee42a48cc9329c686ae6cb2023-04-29T14:56:04ZengElsevierHeliyon2405-84402023-04-0194e15287Association of inferior division MCA stroke location with populations with atrial fibrillation incidenceGanghyun Kim0Emilia Vitti1Melissa D. Stockbridge2Jeffrey L. Saver3Argye E. Hillis4Andreia V. Faria5Department of Neuroscience, Johns Hopkins University, Baltimore, MD, USADepartment of Neurology, School of Medicine, Johns Hopkins University, Baltimore, MD, USADepartment of Neurology, School of Medicine, Johns Hopkins University, Baltimore, MD, USADepartment of Neurology, School of Medicine, University of California, Los Angeles, CA, USADepartment of Neurology, School of Medicine, Johns Hopkins University, Baltimore, MD, USA; Department of Physical Medicine & Rehabilitation, and Department of Cognitive Science, Johns Hopkins University, Baltimore, MD, USADepartment of Radiology, School of Medicine, Johns Hopkins University, Baltimore, MD, USA; Corresponding author.Background and Aim: Considering the anatomical features of Middle Cerebral Artery (MCA) bifurcation, larger emboli are more likely to enter the inferior division over the superior division. Since emboli of cardiac origin are larger on average than emboli of arterial origin, we hypothesize that the infarcts in temporal and parietal lobes are more likely associated to atrial fibrillation than those in the frontal lobes, therefore occurring more often in populations with higher incidence of atrial fibrillation, such as male (compared to women) and white (compared to black) patients.Methods: We included 197 patients with MCA “temporoparietal predominant” infarcts and 105 with “frontal predominant” infarcts. Variations between stroke location (frontal or temporoparietal), sex, and race were examined via Chi-square test.Results: Male patients were more likely than female patients to be afflicted by temporoparietal strokes versus frontal strokes, while white patients had greater likelihood than black patients to be afflicted by temporoparietal strokes versus frontal strokes. Patients with confirmed diagnosis of atrial fibrillation display more temporoparietal strokes compared to frontal strokes.Conclusion: Temporoparietal MCA ischemic strokes occur more frequently in male and white patients: populations with known increased incidence of atrial fibrillation. In addition, population-specific anatomical characteristics of the MCA bifurcation might favor the larger cardiac emboli to enter the inferior division and cause temporoparietal infarcts. This association can help guide search for the most likely etiology of infarcts.http://www.sciencedirect.com/science/article/pii/S2405844023024945StrokeInfarction volumeArterial territoriesMagnetic resonance imagingAtrial fibrillation |
| spellingShingle | Ganghyun Kim Emilia Vitti Melissa D. Stockbridge Jeffrey L. Saver Argye E. Hillis Andreia V. Faria Association of inferior division MCA stroke location with populations with atrial fibrillation incidence Heliyon Stroke Infarction volume Arterial territories Magnetic resonance imaging Atrial fibrillation |
| title | Association of inferior division MCA stroke location with populations with atrial fibrillation incidence |
| title_full | Association of inferior division MCA stroke location with populations with atrial fibrillation incidence |
| title_fullStr | Association of inferior division MCA stroke location with populations with atrial fibrillation incidence |
| title_full_unstemmed | Association of inferior division MCA stroke location with populations with atrial fibrillation incidence |
| title_short | Association of inferior division MCA stroke location with populations with atrial fibrillation incidence |
| title_sort | association of inferior division mca stroke location with populations with atrial fibrillation incidence |
| topic | Stroke Infarction volume Arterial territories Magnetic resonance imaging Atrial fibrillation |
| url | http://www.sciencedirect.com/science/article/pii/S2405844023024945 |
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