Impact of mesoporous silica on the chemical degradation of Praziquantel upon grinding
Praziquantel and Syloid 244 FP (amorphous silicon dioxide) were ground in a vibrational mill in standard conditions ($15^{\prime}$ or $30^{\prime}$ at 25 Hz). Amorphous solid dispersions were obtained in a very short grinding time (15 min), as testified by DSC, PXRD and ESEM analyses. Samples ground...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Académie des sciences
2021-05-01
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| Series: | Comptes Rendus. Chimie |
| Subjects: | |
| Online Access: | https://comptes-rendus.academie-sciences.fr/chimie/articles/10.5802/crchim.82/ |