Delayed esophageal perforation from stereotactic body radiation therapy for locally recurrent central nonsmall cell lung cancer
Stereotactic body radiation therapy (SBRT) is a novel form of external beam radiation therapy. It is used to treat early and locally recurrent nonsmall cell lung cancer (NSLC) in medically inoperable patients. It uses high dose, hypofractionated radiotherapy, with targeting of the tumor by precise s...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2014-01-01
|
| Series: | Lung India |
| Subjects: | |
| Online Access: | http://www.lungindia.com/article.asp?issn=0970-2113;year=2014;volume=31;issue=2;spage=158;epage=160;aulast=Sainathan |
| _version_ | 1811232287566594048 |
|---|---|
| author | Sandeep Sainathan Leester D Wu Shahriyour Andaz |
| author_facet | Sandeep Sainathan Leester D Wu Shahriyour Andaz |
| author_sort | Sandeep Sainathan |
| collection | DOAJ |
| description | Stereotactic body radiation therapy (SBRT) is a novel form of external beam radiation therapy. It is used to treat early and locally recurrent nonsmall cell lung cancer (NSLC) in medically inoperable patients. It uses high dose, hypofractionated radiotherapy, with targeting of the tumor by precise spatial localization, thus minimizing injury to surrounding tissues. It can be safely used to ablate NSLC in both central and peripheral locations. We present two cases of delayed esophageal perforation after SBRT for locally recurrent central NSLC. The perforations occurred several months after the therapy. They were treated with covered esophageal stents, with mortality, due to the perforation in one of the patients. SBRT should be judiciously used to ablate centrally located NSLC and patients who develop episodes of esophagitis during or after SBRT, need to be closely followed with endoscopy to look for esophageal ulcerations. These ulcers should be closely followed for healing as these may degenerate into full thickness perforations several months after SBRT. |
| first_indexed | 2024-04-12T10:59:47Z |
| format | Article |
| id | doaj.art-127504aca69f423eb0c0788abf9e732c |
| institution | Directory Open Access Journal |
| issn | 0970-2113 0974-598X |
| language | English |
| last_indexed | 2024-04-12T10:59:47Z |
| publishDate | 2014-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Lung India |
| spelling | doaj.art-127504aca69f423eb0c0788abf9e732c2022-12-22T03:35:58ZengWolters Kluwer Medknow PublicationsLung India0970-21130974-598X2014-01-0131215816010.4103/0970-2113.129854Delayed esophageal perforation from stereotactic body radiation therapy for locally recurrent central nonsmall cell lung cancerSandeep SainathanLeester D WuShahriyour AndazStereotactic body radiation therapy (SBRT) is a novel form of external beam radiation therapy. It is used to treat early and locally recurrent nonsmall cell lung cancer (NSLC) in medically inoperable patients. It uses high dose, hypofractionated radiotherapy, with targeting of the tumor by precise spatial localization, thus minimizing injury to surrounding tissues. It can be safely used to ablate NSLC in both central and peripheral locations. We present two cases of delayed esophageal perforation after SBRT for locally recurrent central NSLC. The perforations occurred several months after the therapy. They were treated with covered esophageal stents, with mortality, due to the perforation in one of the patients. SBRT should be judiciously used to ablate centrally located NSLC and patients who develop episodes of esophagitis during or after SBRT, need to be closely followed with endoscopy to look for esophageal ulcerations. These ulcers should be closely followed for healing as these may degenerate into full thickness perforations several months after SBRT.http://www.lungindia.com/article.asp?issn=0970-2113;year=2014;volume=31;issue=2;spage=158;epage=160;aulast=SainathanCovered esophageal stentsesophageal perforationlung cancerstereotactic body radiation therapy |
| spellingShingle | Sandeep Sainathan Leester D Wu Shahriyour Andaz Delayed esophageal perforation from stereotactic body radiation therapy for locally recurrent central nonsmall cell lung cancer Lung India Covered esophageal stents esophageal perforation lung cancer stereotactic body radiation therapy |
| title | Delayed esophageal perforation from stereotactic body radiation therapy for locally recurrent central nonsmall cell lung cancer |
| title_full | Delayed esophageal perforation from stereotactic body radiation therapy for locally recurrent central nonsmall cell lung cancer |
| title_fullStr | Delayed esophageal perforation from stereotactic body radiation therapy for locally recurrent central nonsmall cell lung cancer |
| title_full_unstemmed | Delayed esophageal perforation from stereotactic body radiation therapy for locally recurrent central nonsmall cell lung cancer |
| title_short | Delayed esophageal perforation from stereotactic body radiation therapy for locally recurrent central nonsmall cell lung cancer |
| title_sort | delayed esophageal perforation from stereotactic body radiation therapy for locally recurrent central nonsmall cell lung cancer |
| topic | Covered esophageal stents esophageal perforation lung cancer stereotactic body radiation therapy |
| url | http://www.lungindia.com/article.asp?issn=0970-2113;year=2014;volume=31;issue=2;spage=158;epage=160;aulast=Sainathan |
| work_keys_str_mv | AT sandeepsainathan delayedesophagealperforationfromstereotacticbodyradiationtherapyforlocallyrecurrentcentralnonsmallcelllungcancer AT leesterdwu delayedesophagealperforationfromstereotacticbodyradiationtherapyforlocallyrecurrentcentralnonsmallcelllungcancer AT shahriyourandaz delayedesophagealperforationfromstereotacticbodyradiationtherapyforlocallyrecurrentcentralnonsmallcelllungcancer |