Brain type of creatine kinase induces doxorubicin resistance via TGF-β signaling in MDA-MB-231 breast cancer cells

Brain type of creatine kinase induces doxorubicin resistance via TGF-β signaling in MDA-MB-231 breast cancer cells

Brain type of creatine kinase (CKB) regulates energy homeostasis by reversibly transferring phosphate groups between phosphocreatine and ATP at sites of high energy demand. Several types of cancer cells exhibit upregulated CKB expression, but the function of CKB in cancer cells remains unclear. In t...

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Bibliographic Details
Main Authors: Seogho Son, Seung-ah Yoo, KeeSoo Nam, Sunhwa Oh, Kyung-min Lee, Jae Youn Yi, Incheol Shin
Format: Article
Language:English
Published: Taylor & Francis Group 2022-09-01
Series:Animal Cells and Systems
Subjects:
Apoptosis
brain type of creatine kinase (CKB)
doxorubicin
MDA-MB-231
transforming growth factor-β (TGF-β)
Online Access:https://www.tandfonline.com/doi/10.1080/19768354.2022.2107070

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https://www.tandfonline.com/doi/10.1080/19768354.2022.2107070

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