Primary Malignant Melanoma of the Lung: A Case Report
<p>Abstract</p> <p>Background</p> <p>Primary melanoma of the lung is an extremely rare pathological entity and sparsely reported in the literature.</p> <p>Case presentation</p> <p>A case of primary malignant melanoma of the lung in a 41-year-old...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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BMC
2003-11-01
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| Series: | World Journal of Surgical Oncology |
| Subjects: | |
| Online Access: | http://www.wjso.com/content/1/1/26 |
| _version_ | 1811281760094257152 |
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| author | Karagianni Evangelia Zisis Charalambos Dountsis Apostolos Dahabreh Jubrail |
| author_facet | Karagianni Evangelia Zisis Charalambos Dountsis Apostolos Dahabreh Jubrail |
| author_sort | Karagianni Evangelia |
| collection | DOAJ |
| description | <p>Abstract</p> <p>Background</p> <p>Primary melanoma of the lung is an extremely rare pathological entity and sparsely reported in the literature.</p> <p>Case presentation</p> <p>A case of primary malignant melanoma of the lung in a 41-year-old female is reported. The clinical, radiological and histopathological features are discussed. The initial symptom was cough, whereas the chest radiography showed a round opacity of the right lung. The computed tomography of the chest revealed a well-demarcated mass lesion in the right upper lobe. Endobronchial mass causing obstruction of the upper lobar bronchus was the bronchoscopic finding. Patient underwent pneumonectomy. A diagnosis of melanoma was confirmed postoperatively after the immunohistochemistry. Primary nature of the tumour in the lung results from the demonstration of characteristic junctional pattern of melanoma cells beneath the bronchial epithelium on histopathology, and from exclusion of other potential primary sites in the clinical, paraclinical and laboratory examination.</p> <p>Conclusions</p> <p>Primary melanoma of the lung represents a rare pathological entity. Careful interpretation of histopathological information in correlation with all other findings from clinical and paraclinical studies can establish a diagnosis. Follow-up is necessary in order to diagnose potential dissemination or secondary sites of the disease. Due to the small number of cases reported in the literature, there is no experience on the management and the prognosis of the disease, but surgical resection remains the cornerstone of the treatment.</p> |
| first_indexed | 2024-04-13T01:39:24Z |
| format | Article |
| id | doaj.art-128288c6f0104f76acf5293dd386e264 |
| institution | Directory Open Access Journal |
| issn | 1477-7819 |
| language | English |
| last_indexed | 2024-04-13T01:39:24Z |
| publishDate | 2003-11-01 |
| publisher | BMC |
| record_format | Article |
| series | World Journal of Surgical Oncology |
| spelling | doaj.art-128288c6f0104f76acf5293dd386e2642022-12-22T03:08:14ZengBMCWorld Journal of Surgical Oncology1477-78192003-11-01112610.1186/1477-7819-1-26Primary Malignant Melanoma of the Lung: A Case ReportKaragianni EvangeliaZisis CharalambosDountsis ApostolosDahabreh Jubrail<p>Abstract</p> <p>Background</p> <p>Primary melanoma of the lung is an extremely rare pathological entity and sparsely reported in the literature.</p> <p>Case presentation</p> <p>A case of primary malignant melanoma of the lung in a 41-year-old female is reported. The clinical, radiological and histopathological features are discussed. The initial symptom was cough, whereas the chest radiography showed a round opacity of the right lung. The computed tomography of the chest revealed a well-demarcated mass lesion in the right upper lobe. Endobronchial mass causing obstruction of the upper lobar bronchus was the bronchoscopic finding. Patient underwent pneumonectomy. A diagnosis of melanoma was confirmed postoperatively after the immunohistochemistry. Primary nature of the tumour in the lung results from the demonstration of characteristic junctional pattern of melanoma cells beneath the bronchial epithelium on histopathology, and from exclusion of other potential primary sites in the clinical, paraclinical and laboratory examination.</p> <p>Conclusions</p> <p>Primary melanoma of the lung represents a rare pathological entity. Careful interpretation of histopathological information in correlation with all other findings from clinical and paraclinical studies can establish a diagnosis. Follow-up is necessary in order to diagnose potential dissemination or secondary sites of the disease. Due to the small number of cases reported in the literature, there is no experience on the management and the prognosis of the disease, but surgical resection remains the cornerstone of the treatment.</p>http://www.wjso.com/content/1/1/26MalignantmelanomapulmonaryimmunohistochemistrypneumonectomyinterferonHMB-45S-100 |
| spellingShingle | Karagianni Evangelia Zisis Charalambos Dountsis Apostolos Dahabreh Jubrail Primary Malignant Melanoma of the Lung: A Case Report World Journal of Surgical Oncology Malignant melanoma pulmonary immunohistochemistry pneumonectomy interferon HMB-45 S-100 |
| title | Primary Malignant Melanoma of the Lung: A Case Report |
| title_full | Primary Malignant Melanoma of the Lung: A Case Report |
| title_fullStr | Primary Malignant Melanoma of the Lung: A Case Report |
| title_full_unstemmed | Primary Malignant Melanoma of the Lung: A Case Report |
| title_short | Primary Malignant Melanoma of the Lung: A Case Report |
| title_sort | primary malignant melanoma of the lung a case report |
| topic | Malignant melanoma pulmonary immunohistochemistry pneumonectomy interferon HMB-45 S-100 |
| url | http://www.wjso.com/content/1/1/26 |
| work_keys_str_mv | AT karagiannievangelia primarymalignantmelanomaofthelungacasereport AT zisischaralambos primarymalignantmelanomaofthelungacasereport AT dountsisapostolos primarymalignantmelanomaofthelungacasereport AT dahabrehjubrail primarymalignantmelanomaofthelungacasereport |