Ugi post-condensation copper-triggered oxidative cascade towards pyrazoles
Pyrazolidinones were prepared in a two-step sequence starting from α-hydrazonocarboxylic acids. After a four-component Ugi coupling, the resulting hydrazone was engaged in a copper triggered [3 + 2] cycloaddition/aerobic oxidation cascade.
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Beilstein-Institut
2011-09-01
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| Series: | Beilstein Journal of Organic Chemistry |
| Subjects: | |
| Online Access: | https://doi.org/10.3762/bjoc.7.153 |
| _version_ | 1818326319501410304 |
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| author | Aurélie Dos Santos Laurent El Kaim Laurence Grimaud Caroline Ronsseray |
| author_facet | Aurélie Dos Santos Laurent El Kaim Laurence Grimaud Caroline Ronsseray |
| author_sort | Aurélie Dos Santos |
| collection | DOAJ |
| description | Pyrazolidinones were prepared in a two-step sequence starting from α-hydrazonocarboxylic acids. After a four-component Ugi coupling, the resulting hydrazone was engaged in a copper triggered [3 + 2] cycloaddition/aerobic oxidation cascade. |
| first_indexed | 2024-12-13T11:58:29Z |
| format | Article |
| id | doaj.art-128760f5c20d4820b9e4b57d4a909ab3 |
| institution | Directory Open Access Journal |
| issn | 1860-5397 |
| language | English |
| last_indexed | 2024-12-13T11:58:29Z |
| publishDate | 2011-09-01 |
| publisher | Beilstein-Institut |
| record_format | Article |
| series | Beilstein Journal of Organic Chemistry |
| spelling | doaj.art-128760f5c20d4820b9e4b57d4a909ab32022-12-21T23:47:09ZengBeilstein-InstitutBeilstein Journal of Organic Chemistry1860-53972011-09-01711310131410.3762/bjoc.7.1531860-5397-7-153Ugi post-condensation copper-triggered oxidative cascade towards pyrazolesAurélie Dos Santos0Laurent El Kaim1Laurence Grimaud2Caroline Ronsseray3Laboratoire Chimie et Procédés, Laboratoire Chimie et procédés, UMR 7652-DCSO-CNRS- ENSTA-École Polytechnique, École Nationale Supérieure de Techniques Avancées, 32 Bd Victor, Paris 75015, FranceLaboratoire Chimie et Procédés, Laboratoire Chimie et procédés, UMR 7652-DCSO-CNRS- ENSTA-École Polytechnique, École Nationale Supérieure de Techniques Avancées, 32 Bd Victor, Paris 75015, FranceLaboratoire Chimie et Procédés, Laboratoire Chimie et procédés, UMR 7652-DCSO-CNRS- ENSTA-École Polytechnique, École Nationale Supérieure de Techniques Avancées, 32 Bd Victor, Paris 75015, FranceLaboratoire Chimie et Procédés, Laboratoire Chimie et procédés, UMR 7652-DCSO-CNRS- ENSTA-École Polytechnique, École Nationale Supérieure de Techniques Avancées, 32 Bd Victor, Paris 75015, FrancePyrazolidinones were prepared in a two-step sequence starting from α-hydrazonocarboxylic acids. After a four-component Ugi coupling, the resulting hydrazone was engaged in a copper triggered [3 + 2] cycloaddition/aerobic oxidation cascade.https://doi.org/10.3762/bjoc.7.153aerobic oxidationcopper(II)[3 + 2] cycloadditionhydrazoneisocyanidepyrazolidinone |
| spellingShingle | Aurélie Dos Santos Laurent El Kaim Laurence Grimaud Caroline Ronsseray Ugi post-condensation copper-triggered oxidative cascade towards pyrazoles Beilstein Journal of Organic Chemistry aerobic oxidation copper(II) [3 + 2] cycloaddition hydrazone isocyanide pyrazolidinone |
| title | Ugi post-condensation copper-triggered oxidative cascade towards pyrazoles |
| title_full | Ugi post-condensation copper-triggered oxidative cascade towards pyrazoles |
| title_fullStr | Ugi post-condensation copper-triggered oxidative cascade towards pyrazoles |
| title_full_unstemmed | Ugi post-condensation copper-triggered oxidative cascade towards pyrazoles |
| title_short | Ugi post-condensation copper-triggered oxidative cascade towards pyrazoles |
| title_sort | ugi post condensation copper triggered oxidative cascade towards pyrazoles |
| topic | aerobic oxidation copper(II) [3 + 2] cycloaddition hydrazone isocyanide pyrazolidinone |
| url | https://doi.org/10.3762/bjoc.7.153 |
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