Applications of magnetic nanoparticles in biomedical separation and purification
In recent years, nanoparticle formulations utilizing magnetic materials have started gaining more consideration in the biomedical arena due to their inherent superparamagnetic/paramagnetic nature paving ways to develop assays and sensors benefitting mostly magnetic separation technique. Coupled with...
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| Format: | Article |
| Language: | English |
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De Gruyter
2016-06-01
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| Series: | Nanotechnology Reviews |
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| Online Access: | https://doi.org/10.1515/ntrev-2015-0012 |
| _version_ | 1818909318289817600 |
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| author | Yildiz Ibrahim |
| author_facet | Yildiz Ibrahim |
| author_sort | Yildiz Ibrahim |
| collection | DOAJ |
| description | In recent years, nanoparticle formulations utilizing magnetic materials have started gaining more consideration in the biomedical arena due to their inherent superparamagnetic/paramagnetic nature paving ways to develop assays and sensors benefitting mostly magnetic separation technique. Coupled with the developments in the synthetic field in obtaining controlled-sized particles and surface functionalities, a variety of sensitive and selective assays have been developed ranging from detection/separation/enrichment of antibodies, enzymes, proteins, and nucleic acids to whole cells, virus, and pathogens utilizing a variety of signal transduction mechanisms including fluorescence, surface plasmon resonance, and magnetic resonance. In addition to ongoing research in this field, there are already commercialized products engineered to detect and quantify biomolecules with proper surface formulations. Owing to the immensity of applications of magnetic particles, in this article, recent trends in the design and applications of iron oxide nanoparticles will be reviewed. |
| first_indexed | 2024-12-19T22:25:00Z |
| format | Article |
| id | doaj.art-1287fa33866b4357960892ebe9d41e6f |
| institution | Directory Open Access Journal |
| issn | 2191-9089 2191-9097 |
| language | English |
| last_indexed | 2024-12-19T22:25:00Z |
| publishDate | 2016-06-01 |
| publisher | De Gruyter |
| record_format | Article |
| series | Nanotechnology Reviews |
| spelling | doaj.art-1287fa33866b4357960892ebe9d41e6f2022-12-21T20:03:32ZengDe GruyterNanotechnology Reviews2191-90892191-90972016-06-015333134010.1515/ntrev-2015-0012Applications of magnetic nanoparticles in biomedical separation and purificationYildiz Ibrahim0Applied Mathematics and Sciences, Khalifa University, PO Box 127788, Abu Dhabi, UAEIn recent years, nanoparticle formulations utilizing magnetic materials have started gaining more consideration in the biomedical arena due to their inherent superparamagnetic/paramagnetic nature paving ways to develop assays and sensors benefitting mostly magnetic separation technique. Coupled with the developments in the synthetic field in obtaining controlled-sized particles and surface functionalities, a variety of sensitive and selective assays have been developed ranging from detection/separation/enrichment of antibodies, enzymes, proteins, and nucleic acids to whole cells, virus, and pathogens utilizing a variety of signal transduction mechanisms including fluorescence, surface plasmon resonance, and magnetic resonance. In addition to ongoing research in this field, there are already commercialized products engineered to detect and quantify biomolecules with proper surface formulations. Owing to the immensity of applications of magnetic particles, in this article, recent trends in the design and applications of iron oxide nanoparticles will be reviewed.https://doi.org/10.1515/ntrev-2015-0012biosensoriron oxidemagnetic separationnanoparticlessuperparamagnetic particles |
| spellingShingle | Yildiz Ibrahim Applications of magnetic nanoparticles in biomedical separation and purification Nanotechnology Reviews biosensor iron oxide magnetic separation nanoparticles superparamagnetic particles |
| title | Applications of magnetic nanoparticles in biomedical separation and purification |
| title_full | Applications of magnetic nanoparticles in biomedical separation and purification |
| title_fullStr | Applications of magnetic nanoparticles in biomedical separation and purification |
| title_full_unstemmed | Applications of magnetic nanoparticles in biomedical separation and purification |
| title_short | Applications of magnetic nanoparticles in biomedical separation and purification |
| title_sort | applications of magnetic nanoparticles in biomedical separation and purification |
| topic | biosensor iron oxide magnetic separation nanoparticles superparamagnetic particles |
| url | https://doi.org/10.1515/ntrev-2015-0012 |
| work_keys_str_mv | AT yildizibrahim applicationsofmagneticnanoparticlesinbiomedicalseparationandpurification |