Comparative Study on the Distribution of Glucagon-like Peptide-1 (GLP-1)-immunoreactive Cells in the Intestine of Chicken and Ostrich
The distribution of glucagon-like peptide-1 (GLP-1)-immunoreactive cells was investigated in the intestine of the chicken and ostrich. GLP-1-immunoreactive endocrine cells were distributed only in the jejunum and ileum of both avian species. In chicken, these cells had a pyramidal or spindle-like...
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| Format: | Article |
| Language: | English |
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Japan Poultry Science Association
2003-01-01
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| Series: | The Journal of Poultry Science |
| Subjects: | |
| Online Access: | https://www.jstage.jst.go.jp/article/jpsa/40/1/40_1_39/_pdf/-char/en |
| _version_ | 1797816916921810944 |
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| author | Kohzy Hiramatsu Asa Yamasaki Yutaka Karasawa |
| author_facet | Kohzy Hiramatsu Asa Yamasaki Yutaka Karasawa |
| author_sort | Kohzy Hiramatsu |
| collection | DOAJ |
| description | The distribution of glucagon-like peptide-1 (GLP-1)-immunoreactive cells was investigated in the intestine of the chicken and ostrich. GLP-1-immunoreactive endocrine cells were distributed only in the jejunum and ileum of both avian species. In chicken, these cells had a pyramidal or spindle-like shape with a cytoplasmic process and were observed at the lower part of villi and in intestinal crypts. In ostriches, endocrine cells immunoreactive with GLP-1 antiserum showed a flask- or spindle-like shape with a longer cytoplasmic process and were found in the middle and lower parts of intestinal villi. The cytoplasmic process reached to the intestinal lumen in both avian species. The frequencies of occurrence of GLP-1-immunoreactive cells in the jejunum and ileum were 19.71±8.78 and 35.82±13.87, respectively (cell numbers per mucosal area : cells/mm2, mean±SD), in the chicken, and 7.72±5.50 and 6.72±3.24 in the ostrich. The difference in the frequency of occurrence of cells showing GLP-1 immunoreactivity was significant between jejunum and ileum in the chicken, but not in the ostrich. These findings suggest that GLP-1 might be one of the major hormones in the avian intestine. There is, however, a species difference in the distributional pattern of cells containing GLP-1. |
| first_indexed | 2024-03-13T08:44:48Z |
| format | Article |
| id | doaj.art-1288d66c950f40e0a9c9fb02f943918a |
| institution | Directory Open Access Journal |
| issn | 1346-7395 1349-0486 |
| language | English |
| last_indexed | 2024-03-13T08:44:48Z |
| publishDate | 2003-01-01 |
| publisher | Japan Poultry Science Association |
| record_format | Article |
| series | The Journal of Poultry Science |
| spelling | doaj.art-1288d66c950f40e0a9c9fb02f943918a2023-05-30T05:46:30ZengJapan Poultry Science AssociationThe Journal of Poultry Science1346-73951349-04862003-01-01401394410.2141/jpsa.40.39jpsaComparative Study on the Distribution of Glucagon-like Peptide-1 (GLP-1)-immunoreactive Cells in the Intestine of Chicken and OstrichKohzy Hiramatsu0Asa Yamasaki1Yutaka Karasawa2Laboratory of Functional Anatomy and Laboratory of Animal Nutrition, Faculty of Agriculture, Shinshu UniversityLaboratory of Functional Anatomy and Laboratory of Animal Nutrition, Faculty of Agriculture, Shinshu UniversityLaboratory of Functional Anatomy and Laboratory of Animal Nutrition, Faculty of Agriculture, Shinshu UniversityThe distribution of glucagon-like peptide-1 (GLP-1)-immunoreactive cells was investigated in the intestine of the chicken and ostrich. GLP-1-immunoreactive endocrine cells were distributed only in the jejunum and ileum of both avian species. In chicken, these cells had a pyramidal or spindle-like shape with a cytoplasmic process and were observed at the lower part of villi and in intestinal crypts. In ostriches, endocrine cells immunoreactive with GLP-1 antiserum showed a flask- or spindle-like shape with a longer cytoplasmic process and were found in the middle and lower parts of intestinal villi. The cytoplasmic process reached to the intestinal lumen in both avian species. The frequencies of occurrence of GLP-1-immunoreactive cells in the jejunum and ileum were 19.71±8.78 and 35.82±13.87, respectively (cell numbers per mucosal area : cells/mm2, mean±SD), in the chicken, and 7.72±5.50 and 6.72±3.24 in the ostrich. The difference in the frequency of occurrence of cells showing GLP-1 immunoreactivity was significant between jejunum and ileum in the chicken, but not in the ostrich. These findings suggest that GLP-1 might be one of the major hormones in the avian intestine. There is, however, a species difference in the distributional pattern of cells containing GLP-1.https://www.jstage.jst.go.jp/article/jpsa/40/1/40_1_39/_pdf/-char/englucagon-like peptide-1immunohistochemistryintestinechickenostrich |
| spellingShingle | Kohzy Hiramatsu Asa Yamasaki Yutaka Karasawa Comparative Study on the Distribution of Glucagon-like Peptide-1 (GLP-1)-immunoreactive Cells in the Intestine of Chicken and Ostrich The Journal of Poultry Science glucagon-like peptide-1 immunohistochemistry intestine chicken ostrich |
| title | Comparative Study on the Distribution of Glucagon-like Peptide-1 (GLP-1)-immunoreactive Cells in the Intestine of Chicken and Ostrich |
| title_full | Comparative Study on the Distribution of Glucagon-like Peptide-1 (GLP-1)-immunoreactive Cells in the Intestine of Chicken and Ostrich |
| title_fullStr | Comparative Study on the Distribution of Glucagon-like Peptide-1 (GLP-1)-immunoreactive Cells in the Intestine of Chicken and Ostrich |
| title_full_unstemmed | Comparative Study on the Distribution of Glucagon-like Peptide-1 (GLP-1)-immunoreactive Cells in the Intestine of Chicken and Ostrich |
| title_short | Comparative Study on the Distribution of Glucagon-like Peptide-1 (GLP-1)-immunoreactive Cells in the Intestine of Chicken and Ostrich |
| title_sort | comparative study on the distribution of glucagon like peptide 1 glp 1 immunoreactive cells in the intestine of chicken and ostrich |
| topic | glucagon-like peptide-1 immunohistochemistry intestine chicken ostrich |
| url | https://www.jstage.jst.go.jp/article/jpsa/40/1/40_1_39/_pdf/-char/en |
| work_keys_str_mv | AT kohzyhiramatsu comparativestudyonthedistributionofglucagonlikepeptide1glp1immunoreactivecellsintheintestineofchickenandostrich AT asayamasaki comparativestudyonthedistributionofglucagonlikepeptide1glp1immunoreactivecellsintheintestineofchickenandostrich AT yutakakarasawa comparativestudyonthedistributionofglucagonlikepeptide1glp1immunoreactivecellsintheintestineofchickenandostrich |