Are intrinsic neural timescales related to sensory processing? Evidence from abnormal behavioral states
The brain exhibits a complex temporal structure which translates into a hierarchy of distinct neural timescales. An open question is how these intrinsic timescales are related to sensory or motor information processing and whether these dynamics have common patterns in different behavioral states. W...
| Main Authors: | , , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2021-02-01
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| Series: | NeuroImage |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1053811920310648 |
| _version_ | 1818327767930896384 |
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| author | Federico Zilio Javier Gomez-Pilar Shumei Cao Jun Zhang Di Zang Zengxin Qi Jiaxing Tan Tanigawa Hiromi Xuehai Wu Stuart Fogel Zirui Huang Matthias R. Hohmann Tatiana Fomina Matthis Synofzik Moritz Grosse-Wentrup Adrian M. Owen Georg Northoff |
| author_facet | Federico Zilio Javier Gomez-Pilar Shumei Cao Jun Zhang Di Zang Zengxin Qi Jiaxing Tan Tanigawa Hiromi Xuehai Wu Stuart Fogel Zirui Huang Matthias R. Hohmann Tatiana Fomina Matthis Synofzik Moritz Grosse-Wentrup Adrian M. Owen Georg Northoff |
| author_sort | Federico Zilio |
| collection | DOAJ |
| description | The brain exhibits a complex temporal structure which translates into a hierarchy of distinct neural timescales. An open question is how these intrinsic timescales are related to sensory or motor information processing and whether these dynamics have common patterns in different behavioral states. We address these questions by investigating the brain's intrinsic timescales in healthy controls, motor (amyotrophic lateral sclerosis, locked-in syndrome), sensory (anesthesia, unresponsive wakefulness syndrome), and progressive reduction of sensory processing (from awake states over N1, N2, N3). We employed a combination of measures from EEG resting-state data: auto-correlation window (ACW), power spectral density (PSD), and power-law exponent (PLE). Prolonged neural timescales accompanied by a shift towards slower frequencies were observed in the conditions with sensory deficits, but not in conditions with motor deficits. Our results establish that the spontaneous activity's intrinsic neural timescale is related to the neural capacity that specifically supports sensory rather than motor information processing in the healthy brain. |
| first_indexed | 2024-12-13T12:21:31Z |
| format | Article |
| id | doaj.art-1288e261ae9147cf974d94838274dcab |
| institution | Directory Open Access Journal |
| issn | 1095-9572 |
| language | English |
| last_indexed | 2024-12-13T12:21:31Z |
| publishDate | 2021-02-01 |
| publisher | Elsevier |
| record_format | Article |
| series | NeuroImage |
| spelling | doaj.art-1288e261ae9147cf974d94838274dcab2022-12-21T23:46:33ZengElsevierNeuroImage1095-95722021-02-01226117579Are intrinsic neural timescales related to sensory processing? Evidence from abnormal behavioral statesFederico Zilio0Javier Gomez-Pilar1Shumei Cao2Jun Zhang3Di Zang4Zengxin Qi5Jiaxing Tan6Tanigawa Hiromi7Xuehai Wu8Stuart Fogel9Zirui Huang10Matthias R. Hohmann11Tatiana Fomina12Matthis Synofzik13Moritz Grosse-Wentrup14Adrian M. Owen15Georg Northoff16Department of Philosophy, Sociology, Education and Applied Psychology, University of Padova, Padua, Italy; Corresponding author.Biomedical Engineering Group, University of Valladolid, Valladolid, Spain; Centro de Investigación Biomédica en Red en Bioingeniería, Biomateriales y Nanomedicina (CIBER-BBN), Valladolid, SpainDepartment of Anesthesiology, Huashan Hospital, Fudan University, Shanghai, ChinaDepartment of Anesthesiology, Huashan Hospital, Fudan University, Shanghai, ChinaDepartment of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, ChinaDepartment of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, ChinaDepartment of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, ChinaDepartment of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, ChinaDepartment of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, ChinaThe Brain and Mind Institute, Department of Physiology and Pharmacology and the Department of Psychology, University of Western Ontario, CanadaCenter for Consciousness Science, Department of Anesthesiology, University of Michigan Medical School, Ann Arbor, MI, United StatesDepartment for Empirical Inference, Max Planck Institute for Intelligent Systems, Tübingen, GermanyDepartment for Empirical Inference, Max Planck Institute for Intelligent Systems, Tübingen, GermanyDepartment of Neurology, Hertie Institute for Clinical Brain Research, Tübingen, GermanyResearch Group Neuroinformatics, Faculty of Computer Science, University of Vienna, AustriaThe Brain and Mind Institute, Department of Physiology and Pharmacology and the Department of Psychology, University of Western Ontario, CanadaInstitute of Mental Health Research, University of Ottawa, Ottawa, CanadaThe brain exhibits a complex temporal structure which translates into a hierarchy of distinct neural timescales. An open question is how these intrinsic timescales are related to sensory or motor information processing and whether these dynamics have common patterns in different behavioral states. We address these questions by investigating the brain's intrinsic timescales in healthy controls, motor (amyotrophic lateral sclerosis, locked-in syndrome), sensory (anesthesia, unresponsive wakefulness syndrome), and progressive reduction of sensory processing (from awake states over N1, N2, N3). We employed a combination of measures from EEG resting-state data: auto-correlation window (ACW), power spectral density (PSD), and power-law exponent (PLE). Prolonged neural timescales accompanied by a shift towards slower frequencies were observed in the conditions with sensory deficits, but not in conditions with motor deficits. Our results establish that the spontaneous activity's intrinsic neural timescale is related to the neural capacity that specifically supports sensory rather than motor information processing in the healthy brain.http://www.sciencedirect.com/science/article/pii/S1053811920310648Intrinsic neural timescalesAuto-correlation windowUnresponsive wakefulness syndromeAnesthesiaAmyotrophic lateral sclerosis |
| spellingShingle | Federico Zilio Javier Gomez-Pilar Shumei Cao Jun Zhang Di Zang Zengxin Qi Jiaxing Tan Tanigawa Hiromi Xuehai Wu Stuart Fogel Zirui Huang Matthias R. Hohmann Tatiana Fomina Matthis Synofzik Moritz Grosse-Wentrup Adrian M. Owen Georg Northoff Are intrinsic neural timescales related to sensory processing? Evidence from abnormal behavioral states NeuroImage Intrinsic neural timescales Auto-correlation window Unresponsive wakefulness syndrome Anesthesia Amyotrophic lateral sclerosis |
| title | Are intrinsic neural timescales related to sensory processing? Evidence from abnormal behavioral states |
| title_full | Are intrinsic neural timescales related to sensory processing? Evidence from abnormal behavioral states |
| title_fullStr | Are intrinsic neural timescales related to sensory processing? Evidence from abnormal behavioral states |
| title_full_unstemmed | Are intrinsic neural timescales related to sensory processing? Evidence from abnormal behavioral states |
| title_short | Are intrinsic neural timescales related to sensory processing? Evidence from abnormal behavioral states |
| title_sort | are intrinsic neural timescales related to sensory processing evidence from abnormal behavioral states |
| topic | Intrinsic neural timescales Auto-correlation window Unresponsive wakefulness syndrome Anesthesia Amyotrophic lateral sclerosis |
| url | http://www.sciencedirect.com/science/article/pii/S1053811920310648 |
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