Patterning factors during neural progenitor induction determine regional identity and differentiation potential in vitro
The neural tube consists of neural progenitors (NPs) that acquire different characteristics during gestation due to patterning factors. However, the influence of such patterning factors on human pluripotent stem cells (hPSCs) during in vitro neural differentiation is often unclear. This study compar...
Main Authors: | Aishwarya G. Nadadhur, Prisca S. Leferink, Dwayne Holmes, Lisa Hinz, Paulien Cornelissen-Steijger, Lisa Gasparotto, Vivi M. Heine |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2018-10-01
|
Series: | Stem Cell Research |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1873506118302101 |
Similar Items
-
Neuron-Glia Interactions Increase Neuronal Phenotypes in Tuberous Sclerosis Complex Patient iPSC-Derived Models
by: Aishwarya G. Nadadhur, et al.
Published: (2019-01-01) -
Quantitative proteomic analysis of Rett iPSC-derived neuronal progenitors
by: Suzy Varderidou-Minasian, et al.
Published: (2020-05-01) -
A 3D human co-culture to model neuron-astrocyte interactions in tauopathies
by: Kevin L. Batenburg, et al.
Published: (2023-02-01) -
Simplified 3D protocol capable of generating early cortical neuroepithelium
by: Dwayne B. Holmes, et al.
Published: (2017-03-01) -
Differential Maturation of the Two Regulated Secretory Pathways in Human iPSC-Derived Neurons
by: Javier Emperador Melero, et al.
Published: (2017-03-01)