Coconut Shell Liquid Smoke Promotes Burn Wound Healing
The aim of this study was to evaluate burn wound healing activity of coconut shell liquid smoke (CS-LS) in a burn wound animal model. Burn wound–induced mice were treated with CS-LS (CS-LS group), povidone iodine 10% (povidone group), or NaCl 0.9% (NaCl group). Application of CS-LS promoted wound co...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2017-07-01
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| Series: | Journal of Evidence-Based Complementary & Alternative Medicine |
| Online Access: | https://doi.org/10.1177/2156587216674313 |
| _version_ | 1818134965044379648 |
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| author | Vita Murniati Tarawan MD, PhD Kemala Isnainiasih Mantilidewi MD, PhD Ika Miqra Dhini MD, MHS Putri Teesa Radhiyanti MD, MHS Endang Sutedja MD, PhD |
| author_facet | Vita Murniati Tarawan MD, PhD Kemala Isnainiasih Mantilidewi MD, PhD Ika Miqra Dhini MD, MHS Putri Teesa Radhiyanti MD, MHS Endang Sutedja MD, PhD |
| author_sort | Vita Murniati Tarawan MD, PhD |
| collection | DOAJ |
| description | The aim of this study was to evaluate burn wound healing activity of coconut shell liquid smoke (CS-LS) in a burn wound animal model. Burn wound–induced mice were treated with CS-LS (CS-LS group), povidone iodine 10% (povidone group), or NaCl 0.9% (NaCl group). Application of CS-LS promoted wound contraction compared to that of the povidone and NaCl groups ( P < .05). This study showed a positive correlation between the number of fibroblasts and wound contraction. The number of fibroblasts was highest in the CS-LS group, compared to that of the povidone and NaCl groups ( P < .05). In conclusion, CS-LS promotes burn wound healing by one possible mechanism, by increasing the number of fibroblasts. The results indicate that further experimental trials are needed to develop CS-LS as an alternative topical drug for burn wound healing. |
| first_indexed | 2024-12-11T09:16:59Z |
| format | Article |
| id | doaj.art-1290371957c84d9f9a1f137e34faf860 |
| institution | Directory Open Access Journal |
| issn | 2156-5872 2156-5899 |
| language | English |
| last_indexed | 2024-12-11T09:16:59Z |
| publishDate | 2017-07-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Journal of Evidence-Based Complementary & Alternative Medicine |
| spelling | doaj.art-1290371957c84d9f9a1f137e34faf8602022-12-22T01:13:21ZengSAGE PublishingJournal of Evidence-Based Complementary & Alternative Medicine2156-58722156-58992017-07-012210.1177/2156587216674313Coconut Shell Liquid Smoke Promotes Burn Wound HealingVita Murniati Tarawan MD, PhD0Kemala Isnainiasih Mantilidewi MD, PhD1Ika Miqra Dhini MD, MHS2Putri Teesa Radhiyanti MD, MHS3Endang Sutedja MD, PhD4 Universitas Padjadjaran, Bandung, Indonesia Universitas Padjadjaran, Bandung, Indonesia Universitas Padjadjaran, Bandung, Indonesia Universitas Padjadjaran, Bandung, Indonesia Dr. Hasan Sadikin Hospital, Bandung, IndonesiaThe aim of this study was to evaluate burn wound healing activity of coconut shell liquid smoke (CS-LS) in a burn wound animal model. Burn wound–induced mice were treated with CS-LS (CS-LS group), povidone iodine 10% (povidone group), or NaCl 0.9% (NaCl group). Application of CS-LS promoted wound contraction compared to that of the povidone and NaCl groups ( P < .05). This study showed a positive correlation between the number of fibroblasts and wound contraction. The number of fibroblasts was highest in the CS-LS group, compared to that of the povidone and NaCl groups ( P < .05). In conclusion, CS-LS promotes burn wound healing by one possible mechanism, by increasing the number of fibroblasts. The results indicate that further experimental trials are needed to develop CS-LS as an alternative topical drug for burn wound healing.https://doi.org/10.1177/2156587216674313 |
| spellingShingle | Vita Murniati Tarawan MD, PhD Kemala Isnainiasih Mantilidewi MD, PhD Ika Miqra Dhini MD, MHS Putri Teesa Radhiyanti MD, MHS Endang Sutedja MD, PhD Coconut Shell Liquid Smoke Promotes Burn Wound Healing Journal of Evidence-Based Complementary & Alternative Medicine |
| title | Coconut Shell Liquid Smoke Promotes Burn Wound Healing |
| title_full | Coconut Shell Liquid Smoke Promotes Burn Wound Healing |
| title_fullStr | Coconut Shell Liquid Smoke Promotes Burn Wound Healing |
| title_full_unstemmed | Coconut Shell Liquid Smoke Promotes Burn Wound Healing |
| title_short | Coconut Shell Liquid Smoke Promotes Burn Wound Healing |
| title_sort | coconut shell liquid smoke promotes burn wound healing |
| url | https://doi.org/10.1177/2156587216674313 |
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