Analysis of Sleep Macrostructure in Patients Diagnosed with Parkinson’s Disease
Patients diagnosed with Parkinson’s disease present sleep disorders with a higher frequency than the general population. The sleep architecture in these patients shows variations with respect to the normal population, so in this work it was decided to investigate the characteristics of the...
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| Format: | Article |
| Language: | English |
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MDPI AG
2019-01-01
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| Series: | Behavioral Sciences |
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| Online Access: | http://www.mdpi.com/2076-328X/9/1/6 |
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| author | Justa Elizabeth González-Naranjo Maydelin Alfonso-Alfonso Daymet Grass-Fernandez Lilia María Morales-Chacón Ivón Pedroso-Ibáñez Yordanka Ricardo-de la Fe Arnoldo Padrón-Sánchez |
| author_facet | Justa Elizabeth González-Naranjo Maydelin Alfonso-Alfonso Daymet Grass-Fernandez Lilia María Morales-Chacón Ivón Pedroso-Ibáñez Yordanka Ricardo-de la Fe Arnoldo Padrón-Sánchez |
| author_sort | Justa Elizabeth González-Naranjo |
| collection | DOAJ |
| description | Patients diagnosed with Parkinson’s disease present sleep disorders with a higher frequency than the general population. The sleep architecture in these patients shows variations with respect to the normal population, so in this work it was decided to investigate the characteristics of the macroarchitecture of sleep in patients diagnosed with Parkinson’s disease. A polysomnographic study was carried out on 77 patients diagnosed with Parkinson’s disease. All the studies were processed according to the AASM Manual for the Scoring of Sleep and Associated Events v.2.2, and to the criteria of the International Classification of Sleep Disorders 3rd ed. (2014). Processing was carried out using descriptive statistics, as well as non-parametric analysis for comparison between cases and controls. The group of patients showed significant reductions of the N2, N3, and REM sleep stages when compared with a control group, as well as a significant increase in intra-sleep wakefulness. The number of REM–NoREM sleep cycles and sleep efficiency showed marked reduction compared to the control group. There was a statistically significant difference in the macroarchitecture of sleep between patients diagnosed with Parkinson’s disease and healthy controls. |
| first_indexed | 2024-04-13T16:54:42Z |
| format | Article |
| id | doaj.art-129408d8909349c2b8f0b2e1c45c3fb7 |
| institution | Directory Open Access Journal |
| issn | 2076-328X |
| language | English |
| last_indexed | 2024-04-13T16:54:42Z |
| publishDate | 2019-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Behavioral Sciences |
| spelling | doaj.art-129408d8909349c2b8f0b2e1c45c3fb72022-12-22T02:38:51ZengMDPI AGBehavioral Sciences2076-328X2019-01-0191610.3390/bs9010006bs9010006Analysis of Sleep Macrostructure in Patients Diagnosed with Parkinson’s DiseaseJusta Elizabeth González-Naranjo0Maydelin Alfonso-Alfonso1Daymet Grass-Fernandez2Lilia María Morales-Chacón3Ivón Pedroso-Ibáñez4Yordanka Ricardo-de la Fe5Arnoldo Padrón-Sánchez6Neurophysiology Department, International Center for Neurological Restoration, 25th Ave, No 15805, 11300 Havana, CubaNeurophysiology Department, International Center for Neurological Restoration, 25th Ave, No 15805, 11300 Havana, CubaNeurophysiology Department, International Center for Neurological Restoration, 25th Ave, No 15805, 11300 Havana, CubaNeurophysiology Department, International Center for Neurological Restoration, 25th Ave, No 15805, 11300 Havana, CubaNeurology Department, International Center for Neurological Restoration, 25th Ave, No 15805, 11300 Havana, CubaNeurology Department, International Center for Neurological Restoration, 25th Ave, No 15805, 11300 Havana, CubaNeurology Department, International Center for Neurological Restoration, 25th Ave, No 15805, 11300 Havana, CubaPatients diagnosed with Parkinson’s disease present sleep disorders with a higher frequency than the general population. The sleep architecture in these patients shows variations with respect to the normal population, so in this work it was decided to investigate the characteristics of the macroarchitecture of sleep in patients diagnosed with Parkinson’s disease. A polysomnographic study was carried out on 77 patients diagnosed with Parkinson’s disease. All the studies were processed according to the AASM Manual for the Scoring of Sleep and Associated Events v.2.2, and to the criteria of the International Classification of Sleep Disorders 3rd ed. (2014). Processing was carried out using descriptive statistics, as well as non-parametric analysis for comparison between cases and controls. The group of patients showed significant reductions of the N2, N3, and REM sleep stages when compared with a control group, as well as a significant increase in intra-sleep wakefulness. The number of REM–NoREM sleep cycles and sleep efficiency showed marked reduction compared to the control group. There was a statistically significant difference in the macroarchitecture of sleep between patients diagnosed with Parkinson’s disease and healthy controls.http://www.mdpi.com/2076-328X/9/1/6sleep disordersParkinson’s diseasepolysomnography |
| spellingShingle | Justa Elizabeth González-Naranjo Maydelin Alfonso-Alfonso Daymet Grass-Fernandez Lilia María Morales-Chacón Ivón Pedroso-Ibáñez Yordanka Ricardo-de la Fe Arnoldo Padrón-Sánchez Analysis of Sleep Macrostructure in Patients Diagnosed with Parkinson’s Disease Behavioral Sciences sleep disorders Parkinson’s disease polysomnography |
| title | Analysis of Sleep Macrostructure in Patients Diagnosed with Parkinson’s Disease |
| title_full | Analysis of Sleep Macrostructure in Patients Diagnosed with Parkinson’s Disease |
| title_fullStr | Analysis of Sleep Macrostructure in Patients Diagnosed with Parkinson’s Disease |
| title_full_unstemmed | Analysis of Sleep Macrostructure in Patients Diagnosed with Parkinson’s Disease |
| title_short | Analysis of Sleep Macrostructure in Patients Diagnosed with Parkinson’s Disease |
| title_sort | analysis of sleep macrostructure in patients diagnosed with parkinson s disease |
| topic | sleep disorders Parkinson’s disease polysomnography |
| url | http://www.mdpi.com/2076-328X/9/1/6 |
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