NAA1 NICOTINAMIDE RIBOSIDE SUPPLEMENTATION REDUCES AORTIC STIFFNESS AND BLOOD PRESSURE IN MIDDLE-AGED AND OLDER ADULTS

Purpose: Regular calorie restriction (CR) improves endothelial function and lowers aortic stiffness in older mice and humans; however, adherence to sustained CR remains poor, and possibly unsafe in normal weight older adults. Nicotinamide adenine dinucleotide (NAD+) is an important signaling molecul...

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Bibliographic Details
Main Authors: Christopher Martens, Blair Denman, Melissa Mazzo, Michael Armstrong, Nichole Reisdorph, Matthew McQueen, Michel Chonchol, Douglas Seals
Format: Article
Language:English
Published: BMC 2017-12-01
Series:Artery Research
Online Access:https://www.atlantis-press.com/article/125930181/view