The Arabidopsis SWI/SNF protein BAF60 mediates seedling growth control by modulating DNA accessibility
Abstract Background Plant adaptive responses to changing environments involve complex molecular interplays between intrinsic and external signals. Whilst much is known on the signaling components mediating diurnal, light, and temperature controls on plant development, their influence on chromatin-ba...
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| Format: | Article |
| Language: | English |
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BMC
2017-06-01
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| Series: | Genome Biology |
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| Online Access: | http://link.springer.com/article/10.1186/s13059-017-1246-7 |
| _version_ | 1818538596438638592 |
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| author | Teddy Jégu Alaguraj Veluchamy Juan S. Ramirez-Prado Charley Rizzi-Paillet Magalie Perez Anaïs Lhomme David Latrasse Emeline Coleno Serge Vicaire Stéphanie Legras Bernard Jost Martin Rougée Fredy Barneche Catherine Bergounioux Martin Crespi Magdy M. Mahfouz Heribert Hirt Cécile Raynaud Moussa Benhamed |
| author_facet | Teddy Jégu Alaguraj Veluchamy Juan S. Ramirez-Prado Charley Rizzi-Paillet Magalie Perez Anaïs Lhomme David Latrasse Emeline Coleno Serge Vicaire Stéphanie Legras Bernard Jost Martin Rougée Fredy Barneche Catherine Bergounioux Martin Crespi Magdy M. Mahfouz Heribert Hirt Cécile Raynaud Moussa Benhamed |
| author_sort | Teddy Jégu |
| collection | DOAJ |
| description | Abstract Background Plant adaptive responses to changing environments involve complex molecular interplays between intrinsic and external signals. Whilst much is known on the signaling components mediating diurnal, light, and temperature controls on plant development, their influence on chromatin-based transcriptional controls remains poorly explored. Results In this study we show that a SWI/SNF chromatin remodeler subunit, BAF60, represses seedling growth by modulating DNA accessibility of hypocotyl cell size regulatory genes. BAF60 binds nucleosome-free regions of multiple G box-containing genes, opposing in cis the promoting effect of the photomorphogenic and thermomorphogenic regulator Phytochrome Interacting Factor 4 (PIF4) on hypocotyl elongation. Furthermore, BAF60 expression level is regulated in response to light and daily rhythms. Conclusions These results unveil a short path between a chromatin remodeler and a signaling component to fine-tune plant morphogenesis in response to environmental conditions. |
| first_indexed | 2024-12-11T21:31:00Z |
| format | Article |
| id | doaj.art-1298cda180d841b38327c81bee329e93 |
| institution | Directory Open Access Journal |
| issn | 1474-760X |
| language | English |
| last_indexed | 2024-12-11T21:31:00Z |
| publishDate | 2017-06-01 |
| publisher | BMC |
| record_format | Article |
| series | Genome Biology |
| spelling | doaj.art-1298cda180d841b38327c81bee329e932022-12-22T00:50:11ZengBMCGenome Biology1474-760X2017-06-0118111610.1186/s13059-017-1246-7The Arabidopsis SWI/SNF protein BAF60 mediates seedling growth control by modulating DNA accessibilityTeddy Jégu0Alaguraj Veluchamy1Juan S. Ramirez-Prado2Charley Rizzi-Paillet3Magalie Perez4Anaïs Lhomme5David Latrasse6Emeline Coleno7Serge Vicaire8Stéphanie Legras9Bernard Jost10Martin Rougée11Fredy Barneche12Catherine Bergounioux13Martin Crespi14Magdy M. Mahfouz15Heribert Hirt16Cécile Raynaud17Moussa Benhamed18Institut of Plant Sciences Paris-Saclay (IPS2), UMR 9213/UMR1403, CNRS, INRA, Université Paris-Sud, Université d’Evry, Université Paris-Diderot, Sorbonne Paris-CitéDivision of Biological and Environmental Sciences and Engineering, King Abdullah University of Science and TechnologyInstitut of Plant Sciences Paris-Saclay (IPS2), UMR 9213/UMR1403, CNRS, INRA, Université Paris-Sud, Université d’Evry, Université Paris-Diderot, Sorbonne Paris-CitéInstitut of Plant Sciences Paris-Saclay (IPS2), UMR 9213/UMR1403, CNRS, INRA, Université Paris-Sud, Université d’Evry, Université Paris-Diderot, Sorbonne Paris-CitéInstitut of Plant Sciences Paris-Saclay (IPS2), UMR 9213/UMR1403, CNRS, INRA, Université Paris-Sud, Université d’Evry, Université Paris-Diderot, Sorbonne Paris-CitéInstitut of Plant Sciences Paris-Saclay (IPS2), UMR 9213/UMR1403, CNRS, INRA, Université Paris-Sud, Université d’Evry, Université Paris-Diderot, Sorbonne Paris-CitéInstitut of Plant Sciences Paris-Saclay (IPS2), UMR 9213/UMR1403, CNRS, INRA, Université Paris-Sud, Université d’Evry, Université Paris-Diderot, Sorbonne Paris-CitéInstitut of Plant Sciences Paris-Saclay (IPS2), UMR 9213/UMR1403, CNRS, INRA, Université Paris-Sud, Université d’Evry, Université Paris-Diderot, Sorbonne Paris-CitéPlateforme Biopuces et séquençage, IGBMCPlateforme Biopuces et séquençage, IGBMCPlateforme Biopuces et séquençage, IGBMCEcole Normale Supérieure, PSL Research University, Institut de Biologie de l’Ecole Normale Supérieure (IBENS), CNRS UMR 8197, INSERM U1024Ecole Normale Supérieure, PSL Research University, Institut de Biologie de l’Ecole Normale Supérieure (IBENS), CNRS UMR 8197, INSERM U1024Institut of Plant Sciences Paris-Saclay (IPS2), UMR 9213/UMR1403, CNRS, INRA, Université Paris-Sud, Université d’Evry, Université Paris-Diderot, Sorbonne Paris-CitéInstitut of Plant Sciences Paris-Saclay (IPS2), UMR 9213/UMR1403, CNRS, INRA, Université Paris-Sud, Université d’Evry, Université Paris-Diderot, Sorbonne Paris-CitéDivision of Biological and Environmental Sciences and Engineering, King Abdullah University of Science and TechnologyInstitut of Plant Sciences Paris-Saclay (IPS2), UMR 9213/UMR1403, CNRS, INRA, Université Paris-Sud, Université d’Evry, Université Paris-Diderot, Sorbonne Paris-CitéInstitut of Plant Sciences Paris-Saclay (IPS2), UMR 9213/UMR1403, CNRS, INRA, Université Paris-Sud, Université d’Evry, Université Paris-Diderot, Sorbonne Paris-CitéInstitut of Plant Sciences Paris-Saclay (IPS2), UMR 9213/UMR1403, CNRS, INRA, Université Paris-Sud, Université d’Evry, Université Paris-Diderot, Sorbonne Paris-CitéAbstract Background Plant adaptive responses to changing environments involve complex molecular interplays between intrinsic and external signals. Whilst much is known on the signaling components mediating diurnal, light, and temperature controls on plant development, their influence on chromatin-based transcriptional controls remains poorly explored. Results In this study we show that a SWI/SNF chromatin remodeler subunit, BAF60, represses seedling growth by modulating DNA accessibility of hypocotyl cell size regulatory genes. BAF60 binds nucleosome-free regions of multiple G box-containing genes, opposing in cis the promoting effect of the photomorphogenic and thermomorphogenic regulator Phytochrome Interacting Factor 4 (PIF4) on hypocotyl elongation. Furthermore, BAF60 expression level is regulated in response to light and daily rhythms. Conclusions These results unveil a short path between a chromatin remodeler and a signaling component to fine-tune plant morphogenesis in response to environmental conditions.http://link.springer.com/article/10.1186/s13059-017-1246-7SWI/SNFChromatinMorphogenesisPhytochrome Interacting FactorG-boxDNA accessibility |
| spellingShingle | Teddy Jégu Alaguraj Veluchamy Juan S. Ramirez-Prado Charley Rizzi-Paillet Magalie Perez Anaïs Lhomme David Latrasse Emeline Coleno Serge Vicaire Stéphanie Legras Bernard Jost Martin Rougée Fredy Barneche Catherine Bergounioux Martin Crespi Magdy M. Mahfouz Heribert Hirt Cécile Raynaud Moussa Benhamed The Arabidopsis SWI/SNF protein BAF60 mediates seedling growth control by modulating DNA accessibility Genome Biology SWI/SNF Chromatin Morphogenesis Phytochrome Interacting Factor G-box DNA accessibility |
| title | The Arabidopsis SWI/SNF protein BAF60 mediates seedling growth control by modulating DNA accessibility |
| title_full | The Arabidopsis SWI/SNF protein BAF60 mediates seedling growth control by modulating DNA accessibility |
| title_fullStr | The Arabidopsis SWI/SNF protein BAF60 mediates seedling growth control by modulating DNA accessibility |
| title_full_unstemmed | The Arabidopsis SWI/SNF protein BAF60 mediates seedling growth control by modulating DNA accessibility |
| title_short | The Arabidopsis SWI/SNF protein BAF60 mediates seedling growth control by modulating DNA accessibility |
| title_sort | arabidopsis swi snf protein baf60 mediates seedling growth control by modulating dna accessibility |
| topic | SWI/SNF Chromatin Morphogenesis Phytochrome Interacting Factor G-box DNA accessibility |
| url | http://link.springer.com/article/10.1186/s13059-017-1246-7 |
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