Hubungan Antara Nilai Neutrophil-to-Lymphocyte Ratio (NLR) dengan Kadar Procalcitonin (PCT) pada Pasien COVID-19 di Kabupaten Jember

The neutrophil-to-lymphocyte ratio (NLR) and Procalcitonin (PCT) are biomarkers that represent inflammatory activity and immune status as predictors for the prognosis of COVID-19 patients. NLR values and PCT levels are positively correlated with the severity of COVID-19, but the relationship between...

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Main Authors: Sofia Yusnur Rafida, Hairrudin Hairrudin, Muhammad Hasan
Format: Article
Language:English
Published: Universitas Andalas 2022-12-01
Series:Jurnal Kesehatan Andalas
Online Access:http://jurnal.fk.unand.ac.id/index.php/jka/article/view/1999
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author Sofia Yusnur Rafida
Hairrudin Hairrudin
Muhammad Hasan
author_facet Sofia Yusnur Rafida
Hairrudin Hairrudin
Muhammad Hasan
author_sort Sofia Yusnur Rafida
collection DOAJ
description The neutrophil-to-lymphocyte ratio (NLR) and Procalcitonin (PCT) are biomarkers that represent inflammatory activity and immune status as predictors for the prognosis of COVID-19 patients. NLR values and PCT levels are positively correlated with the severity of COVID-19, but the relationship between the two biomarkers is unclear. Objectives: To analyzed the correlation between NLR values and PCT levels in COVID-19 patients in Jember Regency. Methods: This cross-sectional analytic observational study, conducted from March to April 2022, took data from 444 confirmed COVID-19 patients at the Jember Clinic Plantation Hospital. Secondary data were obtained from medical records of inpatients for the period January–December 2021. Results: The average NLR value was 8.58, while the average PCT level was 0.43 ng/mL. The results of the Spearman Correlation Analysis showed a positive correlation between NLR values and PCT levels in COVID-19 patients in the Jember Regency with a p-value = 0.00 and a moderate degree of correlation with an r count of 0.41. Conclusion: There is a positive correlation between NLR values and PCT levels for COVID-19 patients in Jember Regency. It is necessary to carry out routine NLR and PCT examinations to consider predictors of disease severity and prognosis in COVID-19 patients. Keywords:  COVID-19, NLR, PCT
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spelling doaj.art-1299bc1f43aa444bb9f9353539d2ebbb2023-11-24T03:28:12ZengUniversitas AndalasJurnal Kesehatan Andalas2301-74062615-11382022-12-01112879410.25077/jka.v11i2.19991219Hubungan Antara Nilai Neutrophil-to-Lymphocyte Ratio (NLR) dengan Kadar Procalcitonin (PCT) pada Pasien COVID-19 di Kabupaten JemberSofia Yusnur Rafida0Hairrudin Hairrudin1Muhammad Hasan2Fakultas Kedokteran, Universitas JemberFakultas Kedokteran, Universitas JemberFakultas Kedokteran, Universitas JemberThe neutrophil-to-lymphocyte ratio (NLR) and Procalcitonin (PCT) are biomarkers that represent inflammatory activity and immune status as predictors for the prognosis of COVID-19 patients. NLR values and PCT levels are positively correlated with the severity of COVID-19, but the relationship between the two biomarkers is unclear. Objectives: To analyzed the correlation between NLR values and PCT levels in COVID-19 patients in Jember Regency. Methods: This cross-sectional analytic observational study, conducted from March to April 2022, took data from 444 confirmed COVID-19 patients at the Jember Clinic Plantation Hospital. Secondary data were obtained from medical records of inpatients for the period January–December 2021. Results: The average NLR value was 8.58, while the average PCT level was 0.43 ng/mL. The results of the Spearman Correlation Analysis showed a positive correlation between NLR values and PCT levels in COVID-19 patients in the Jember Regency with a p-value = 0.00 and a moderate degree of correlation with an r count of 0.41. Conclusion: There is a positive correlation between NLR values and PCT levels for COVID-19 patients in Jember Regency. It is necessary to carry out routine NLR and PCT examinations to consider predictors of disease severity and prognosis in COVID-19 patients. Keywords:  COVID-19, NLR, PCThttp://jurnal.fk.unand.ac.id/index.php/jka/article/view/1999
spellingShingle Sofia Yusnur Rafida
Hairrudin Hairrudin
Muhammad Hasan
Hubungan Antara Nilai Neutrophil-to-Lymphocyte Ratio (NLR) dengan Kadar Procalcitonin (PCT) pada Pasien COVID-19 di Kabupaten Jember
Jurnal Kesehatan Andalas
title Hubungan Antara Nilai Neutrophil-to-Lymphocyte Ratio (NLR) dengan Kadar Procalcitonin (PCT) pada Pasien COVID-19 di Kabupaten Jember
title_full Hubungan Antara Nilai Neutrophil-to-Lymphocyte Ratio (NLR) dengan Kadar Procalcitonin (PCT) pada Pasien COVID-19 di Kabupaten Jember
title_fullStr Hubungan Antara Nilai Neutrophil-to-Lymphocyte Ratio (NLR) dengan Kadar Procalcitonin (PCT) pada Pasien COVID-19 di Kabupaten Jember
title_full_unstemmed Hubungan Antara Nilai Neutrophil-to-Lymphocyte Ratio (NLR) dengan Kadar Procalcitonin (PCT) pada Pasien COVID-19 di Kabupaten Jember
title_short Hubungan Antara Nilai Neutrophil-to-Lymphocyte Ratio (NLR) dengan Kadar Procalcitonin (PCT) pada Pasien COVID-19 di Kabupaten Jember
title_sort hubungan antara nilai neutrophil to lymphocyte ratio nlr dengan kadar procalcitonin pct pada pasien covid 19 di kabupaten jember
url http://jurnal.fk.unand.ac.id/index.php/jka/article/view/1999
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