Memory and relatedness of transcriptional activity in mammalian cell lineages
Phenotypically identical mammalian cells often display considerable variability in transcript levels of individual genes. Here the authors document how different genes propagate their expression levels in cell lineages and suggest a potential role of transcriptional memory for generating spatial pat...
Main Authors: | Nicholas E. Phillips, Aleksandra Mandic, Saeed Omidi, Felix Naef, David M. Suter |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2019-03-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-019-09189-8 |
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