Paracrine mechanisms in early differentiation of human pluripotent stem cells: Insights from a mathematical model

Paracrine mechanisms in early differentiation of human pluripotent stem cells: Insights from a mathematical model

With their capability to self-renew and differentiate into derivatives of all three germ layers, human pluripotent stem cells (hPSCs) offer a unique model to study aspects of human development in vitro. Directed differentiation towards mesendodermal lineages is a complex process, involving transitio...

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Bibliographic Details
Main Authors:	Erika Gaspari, Annika Franke, Diana Robles-Diaz, Robert Zweigerdt, Ingo Roeder, Thomas Zerjatke, Henning Kempf
Format:	Article
Language:	English
Published:	Elsevier 2018-10-01
Series:	Stem Cell Research
Online Access:	http://www.sciencedirect.com/science/article/pii/S1873506118302071

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