CAA-derived IL-6 induced M2 macrophage polarization by activating STAT3

CAA-derived IL-6 induced M2 macrophage polarization by activating STAT3

Abstract Background Tumor-associated macrophages (TAMs) are the most abundant types of immune cells in the tumor microenvironment (TME) of breast cancer (BC). TAMs usually exhibit an M2 phenotype and promote tumor progression by facilitating immunosuppression. This study aimed to investigate the eff...

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Bibliographic Details
Main Authors: Chongru Zhao, Ning Zeng, Xiaomei Zhou, Yufang Tan, Yichen Wang, Jun Zhang, Yiping Wu, Qi Zhang
Format: Article
Language:English
Published: BMC 2023-05-01
Series:BMC Cancer
Subjects:
Breast cancer
Cancer-associated adipocytes
IL-6
STAT3
Macrophages
Online Access:https://doi.org/10.1186/s12885-023-10826-1

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