4168 Understanding ECM-Based Drug Resistivity in Breast Cancer
OBJECTIVES/GOALS: Cell-cell (CC) and cell-matrix interactions (CM) are known to affect drug sensitivity of cancer cells, but are not effectively recapitulated using 2D platforms. This research aims to determine how cell and matrix interactions confer drug resistivity in 3 distinct culturing models:...
Main Authors: | Sarah Libring, Aparna Shinde, Miad Boodaghidizaji, Alexandra Plummer, Arezoo Ardekani, Michael Wendt, Luis Solorio |
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Format: | Article |
Language: | English |
Published: |
Cambridge University Press
2020-06-01
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Series: | Journal of Clinical and Translational Science |
Online Access: | https://www.cambridge.org/core/product/identifier/S2059866120003465/type/journal_article |
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