Mining Indole Alkaloid Synthesis Gene Clusters from Genomes of 53 <i>Claviceps</i> Strains Revealed Redundant Gene Copies and an Approximate Evolutionary Hourglass Model

Mining Indole Alkaloid Synthesis Gene Clusters from Genomes of 53 <i>Claviceps</i> Strains Revealed Redundant Gene Copies and an Approximate Evolutionary Hourglass Model

Ergot fungi (<i>Claviceps</i> spp.) are infamous for producing sclerotia containing a wide spectrum of ergot alkaloids (EA) toxic to humans and animals, making them nefarious villains in the agricultural and food industries, but also treasures for pharmaceuticals. In addition to three cl...

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Bibliographic Details
Main Authors: Miao Liu, Wendy Findlay, Jeremy Dettman, Stephen A. Wyka, Kirk Broders, Parivash Shoukouhi, Kasia Dadej, Miroslav Kolařík, Arpeace Basnyat, Jim G. Menzies
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Toxins
Subjects:
ergot alkaloids
ergot fungi
gene divergence
gene diversity
indole diterpenes
phylogeny
Online Access:https://www.mdpi.com/2072-6651/13/11/799

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