Primary glaucoma surgery in Fuchs’ heterochromic uveitis: a comparison of trabeculectomy versus deep sclerectomy

Background: Deep sclerectomy offers the potential advantage of less postoperative inflammation and better survival in Fuchs’ patients. The aim of this study was to compare survival and safety profiles of Fuchs’ heterochromic uveitis patients undergoing trabeculectomy or deep sclerectomy. Methods: A...

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Main Authors: Andrew Walkden, Karl Mercieca, Divya Perumal, Nitin Anand
Format: Article
Language:English
Published: SAGE Publishing 2019-08-01
Series:Therapeutic Advances in Ophthalmology
Online Access:https://doi.org/10.1177/2515841419869761
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author Andrew Walkden
Karl Mercieca
Divya Perumal
Nitin Anand
author_facet Andrew Walkden
Karl Mercieca
Divya Perumal
Nitin Anand
author_sort Andrew Walkden
collection DOAJ
description Background: Deep sclerectomy offers the potential advantage of less postoperative inflammation and better survival in Fuchs’ patients. The aim of this study was to compare survival and safety profiles of Fuchs’ heterochromic uveitis patients undergoing trabeculectomy or deep sclerectomy. Methods: A retrospective study was conducted of two separate cohorts who had undergone either trabeculectomy or deep sclerectomy. Patient demographics, best-corrected visual acuity, intraocular pressure, antimetabolite used, postoperative complications and subsequent procedures were analysed. Results: In total, 13 trabeculectomy patients and 14 deep sclerectomy patients were included. Mean preoperative intraocular pressure was similar at 30.1 mmHg in the trabeculectomy group and 35.9 mmHg in the deep sclerectomy group, with no significant difference between the two ( p  = 0.22). Kaplan–Meier survival outcomes for success at <22 mmHg and <19 mmHg showed no significant differences between the groups and this was also the case for intraocular pressure at 3 years (analysis of variance; p  = 0.47). Conclusion: Both procedures appear to have similar efficacy and safety profiles, suggesting that both are effective.
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spelling doaj.art-12afc18d426d408dbbb230f407deafb92022-12-21T19:33:03ZengSAGE PublishingTherapeutic Advances in Ophthalmology2515-84142019-08-011110.1177/2515841419869761Primary glaucoma surgery in Fuchs’ heterochromic uveitis: a comparison of trabeculectomy versus deep sclerectomyAndrew WalkdenKarl MerciecaDivya PerumalNitin AnandBackground: Deep sclerectomy offers the potential advantage of less postoperative inflammation and better survival in Fuchs’ patients. The aim of this study was to compare survival and safety profiles of Fuchs’ heterochromic uveitis patients undergoing trabeculectomy or deep sclerectomy. Methods: A retrospective study was conducted of two separate cohorts who had undergone either trabeculectomy or deep sclerectomy. Patient demographics, best-corrected visual acuity, intraocular pressure, antimetabolite used, postoperative complications and subsequent procedures were analysed. Results: In total, 13 trabeculectomy patients and 14 deep sclerectomy patients were included. Mean preoperative intraocular pressure was similar at 30.1 mmHg in the trabeculectomy group and 35.9 mmHg in the deep sclerectomy group, with no significant difference between the two ( p  = 0.22). Kaplan–Meier survival outcomes for success at <22 mmHg and <19 mmHg showed no significant differences between the groups and this was also the case for intraocular pressure at 3 years (analysis of variance; p  = 0.47). Conclusion: Both procedures appear to have similar efficacy and safety profiles, suggesting that both are effective.https://doi.org/10.1177/2515841419869761
spellingShingle Andrew Walkden
Karl Mercieca
Divya Perumal
Nitin Anand
Primary glaucoma surgery in Fuchs’ heterochromic uveitis: a comparison of trabeculectomy versus deep sclerectomy
Therapeutic Advances in Ophthalmology
title Primary glaucoma surgery in Fuchs’ heterochromic uveitis: a comparison of trabeculectomy versus deep sclerectomy
title_full Primary glaucoma surgery in Fuchs’ heterochromic uveitis: a comparison of trabeculectomy versus deep sclerectomy
title_fullStr Primary glaucoma surgery in Fuchs’ heterochromic uveitis: a comparison of trabeculectomy versus deep sclerectomy
title_full_unstemmed Primary glaucoma surgery in Fuchs’ heterochromic uveitis: a comparison of trabeculectomy versus deep sclerectomy
title_short Primary glaucoma surgery in Fuchs’ heterochromic uveitis: a comparison of trabeculectomy versus deep sclerectomy
title_sort primary glaucoma surgery in fuchs heterochromic uveitis a comparison of trabeculectomy versus deep sclerectomy
url https://doi.org/10.1177/2515841419869761
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