Recent Advances in the Application of Nanozymes in Amperometric Sensors: A Review
Amperometric sensors evaluate current changes that occur as a result of redox reactions under constant applied potential. These changes in current intensity are stoichiometrically related to the concentration of analytes. Owing to their unique features, such as fast reaction velocity, high specifici...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-04-01
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| Series: | Chemosensors |
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| Online Access: | https://www.mdpi.com/2227-9040/11/4/233 |
| _version_ | 1827745486869626880 |
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| author | Liu Tong Lina Wu Enben Su Yan Li Ning Gu |
| author_facet | Liu Tong Lina Wu Enben Su Yan Li Ning Gu |
| author_sort | Liu Tong |
| collection | DOAJ |
| description | Amperometric sensors evaluate current changes that occur as a result of redox reactions under constant applied potential. These changes in current intensity are stoichiometrically related to the concentration of analytes. Owing to their unique features, such as fast reaction velocity, high specificity, abundant existence in nature, and feasibility to be immobilized, enzymes are widely used by researchers to improve the performance of amperometric sensors. Unfortunately, natural enzymes have intrinsic disadvantages due to their protein structures. To overcome these proteinic drawbacks, scientists have developed nanozymes, which are nanomaterials with enzymatic properties. As the result of significant advances in materiology and analytical science, great progress has been achieved in the development of nanozyme-based amperometric sensors with outstanding performance. To highlight achievements made in recent years, we first summarize the development directions of nanozyme-based amperometric sensors. Then, H<sub>2</sub>O<sub>2</sub> sensors, glucose sensors, sensors combining natural enzymes with nanozymes, and sensors targeting untraditional specific targets will be introduced in detail. Finally, the current challenges regarding the nanozymes utilized in amperometric sensors are discussed and future research directions in this area are suggested. |
| first_indexed | 2024-03-11T05:07:43Z |
| format | Article |
| id | doaj.art-12b147a9a96c4cdfb8a683c2923f428d |
| institution | Directory Open Access Journal |
| issn | 2227-9040 |
| language | English |
| last_indexed | 2024-03-11T05:07:43Z |
| publishDate | 2023-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Chemosensors |
| spelling | doaj.art-12b147a9a96c4cdfb8a683c2923f428d2023-11-17T18:44:46ZengMDPI AGChemosensors2227-90402023-04-0111423310.3390/chemosensors11040233Recent Advances in the Application of Nanozymes in Amperometric Sensors: A ReviewLiu Tong0Lina Wu1Enben Su2Yan Li3Ning Gu4State Key Laboratory of Bioelectronics, Jiangsu Key Laboratory for Biomaterials and Devices, School of Biological Science and Medical Engineering, Southeast University, Nanjing 210009, ChinaGetein Biotechnology Co., Ltd., Nanjing 211505, ChinaGetein Biotechnology Co., Ltd., Nanjing 211505, ChinaState Key Laboratory of Bioelectronics, Jiangsu Key Laboratory for Biomaterials and Devices, School of Biological Science and Medical Engineering, Southeast University, Nanjing 210009, ChinaState Key Laboratory of Bioelectronics, Jiangsu Key Laboratory for Biomaterials and Devices, School of Biological Science and Medical Engineering, Southeast University, Nanjing 210009, ChinaAmperometric sensors evaluate current changes that occur as a result of redox reactions under constant applied potential. These changes in current intensity are stoichiometrically related to the concentration of analytes. Owing to their unique features, such as fast reaction velocity, high specificity, abundant existence in nature, and feasibility to be immobilized, enzymes are widely used by researchers to improve the performance of amperometric sensors. Unfortunately, natural enzymes have intrinsic disadvantages due to their protein structures. To overcome these proteinic drawbacks, scientists have developed nanozymes, which are nanomaterials with enzymatic properties. As the result of significant advances in materiology and analytical science, great progress has been achieved in the development of nanozyme-based amperometric sensors with outstanding performance. To highlight achievements made in recent years, we first summarize the development directions of nanozyme-based amperometric sensors. Then, H<sub>2</sub>O<sub>2</sub> sensors, glucose sensors, sensors combining natural enzymes with nanozymes, and sensors targeting untraditional specific targets will be introduced in detail. Finally, the current challenges regarding the nanozymes utilized in amperometric sensors are discussed and future research directions in this area are suggested.https://www.mdpi.com/2227-9040/11/4/233amperometric sensorsH<sub>2</sub>O<sub>2</sub> sensorglucose sensornanozymeminireview |
| spellingShingle | Liu Tong Lina Wu Enben Su Yan Li Ning Gu Recent Advances in the Application of Nanozymes in Amperometric Sensors: A Review Chemosensors amperometric sensors H<sub>2</sub>O<sub>2</sub> sensor glucose sensor nanozyme minireview |
| title | Recent Advances in the Application of Nanozymes in Amperometric Sensors: A Review |
| title_full | Recent Advances in the Application of Nanozymes in Amperometric Sensors: A Review |
| title_fullStr | Recent Advances in the Application of Nanozymes in Amperometric Sensors: A Review |
| title_full_unstemmed | Recent Advances in the Application of Nanozymes in Amperometric Sensors: A Review |
| title_short | Recent Advances in the Application of Nanozymes in Amperometric Sensors: A Review |
| title_sort | recent advances in the application of nanozymes in amperometric sensors a review |
| topic | amperometric sensors H<sub>2</sub>O<sub>2</sub> sensor glucose sensor nanozyme minireview |
| url | https://www.mdpi.com/2227-9040/11/4/233 |
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