Bone lesion in Adult T Cell Lymphoma Leukemia
A 57-year-old man from Khorasan Razavi presented with severe hypercalsemia and fever, with tempreture up to 40°C, over a 2-week period. He also had severe headache and generalized bone pain. He was admitted and treated for hypercalcemia. After two days hypercalcemia and fever were controlled and bon...
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| Format: | Article |
| Language: | English |
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The Pan African Medical Journal
2013-11-01
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| Series: | The Pan African Medical Journal |
| Subjects: | |
| Online Access: |
https://www.panafrican-med-journal.com/content/article/16/76/pdf/76.pdf
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| _version_ | 1818500437904457728 |
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| author | Zahra Mozaheb |
| author_facet | Zahra Mozaheb |
| author_sort | Zahra Mozaheb |
| collection | DOAJ |
| description | A 57-year-old man from Khorasan Razavi presented with severe hypercalsemia and fever, with tempreture up to 40°C, over a 2-week period. He also had severe headache and generalized bone pain. He was admitted and treated for hypercalcemia. After two days hypercalcemia and fever were controlled and bone pain decreased mildly but his headache continued severely. At first day of admission he was not anemic but one week later he became anemic and thrombocytopenic with atytipical lymphocyte in peripheral blood smear. During patient assessment we found, hyperuricemia, elevated ESR,CRP and LDH. Skeletal radiographies showed severe lytic bone lesion, and brain CT scan was normal. Based on these data, bone marrow exam was done and serum anti HTLV1 was requested. After 3 days we noticed several depressions on the scalp and forehead of the patient because of severe bone resorption. Bone marrow exam showed a patchy lymphocyte infiltration, and serum anti HTLV1 antibody was positive. CD4 also was positive in flowcytomery. All this findings were compatible with Adult T cell Lymphoma Leukemia secondary to HTLV1 infection which is endemic in Khorasan Razavi, Iran. The patient was died before beginning of induction therapy. |
| first_indexed | 2024-12-10T20:42:44Z |
| format | Article |
| id | doaj.art-12b3f4dedac64b2f8a5a5528c72b6733 |
| institution | Directory Open Access Journal |
| issn | 1937-8688 1937-8688 |
| language | English |
| last_indexed | 2024-12-10T20:42:44Z |
| publishDate | 2013-11-01 |
| publisher | The Pan African Medical Journal |
| record_format | Article |
| series | The Pan African Medical Journal |
| spelling | doaj.art-12b3f4dedac64b2f8a5a5528c72b67332022-12-22T01:34:19ZengThe Pan African Medical JournalThe Pan African Medical Journal1937-86881937-86882013-11-01167610.11604/pamj.2013.16.76.27062706Bone lesion in Adult T Cell Lymphoma LeukemiaZahra MozahebA 57-year-old man from Khorasan Razavi presented with severe hypercalsemia and fever, with tempreture up to 40°C, over a 2-week period. He also had severe headache and generalized bone pain. He was admitted and treated for hypercalcemia. After two days hypercalcemia and fever were controlled and bone pain decreased mildly but his headache continued severely. At first day of admission he was not anemic but one week later he became anemic and thrombocytopenic with atytipical lymphocyte in peripheral blood smear. During patient assessment we found, hyperuricemia, elevated ESR,CRP and LDH. Skeletal radiographies showed severe lytic bone lesion, and brain CT scan was normal. Based on these data, bone marrow exam was done and serum anti HTLV1 was requested. After 3 days we noticed several depressions on the scalp and forehead of the patient because of severe bone resorption. Bone marrow exam showed a patchy lymphocyte infiltration, and serum anti HTLV1 antibody was positive. CD4 also was positive in flowcytomery. All this findings were compatible with Adult T cell Lymphoma Leukemia secondary to HTLV1 infection which is endemic in Khorasan Razavi, Iran. The patient was died before beginning of induction therapy. https://www.panafrican-med-journal.com/content/article/16/76/pdf/76.pdf bone lesionadult t cell lymphoma leukemialytic bone lesionhtlv1iran |
| spellingShingle | Zahra Mozaheb Bone lesion in Adult T Cell Lymphoma Leukemia The Pan African Medical Journal bone lesion adult t cell lymphoma leukemia lytic bone lesion htlv1 iran |
| title | Bone lesion in Adult T Cell Lymphoma Leukemia |
| title_full | Bone lesion in Adult T Cell Lymphoma Leukemia |
| title_fullStr | Bone lesion in Adult T Cell Lymphoma Leukemia |
| title_full_unstemmed | Bone lesion in Adult T Cell Lymphoma Leukemia |
| title_short | Bone lesion in Adult T Cell Lymphoma Leukemia |
| title_sort | bone lesion in adult t cell lymphoma leukemia |
| topic | bone lesion adult t cell lymphoma leukemia lytic bone lesion htlv1 iran |
| url |
https://www.panafrican-med-journal.com/content/article/16/76/pdf/76.pdf
|
| work_keys_str_mv | AT zahramozaheb bonelesioninadulttcelllymphomaleukemia |