Nanoplasmonic Strip Test for Salivary Glucose Monitoring
Nowadays, there is an increasing interest in Point-of-care (POC) devices for the noninvasive glucose assessment. Despite the recent progress in glucose self-monitoring, commercially available devices still use invasive samples such as blood or interstitial fluids, and they are not equipment-free and...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-12-01
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| Series: | Nanomaterials |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2079-4991/12/1/105 |
| _version_ | 1797498100739211264 |
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| author | Helena Torné-Morató Paolo Donati Pier Paolo Pompa |
| author_facet | Helena Torné-Morató Paolo Donati Pier Paolo Pompa |
| author_sort | Helena Torné-Morató |
| collection | DOAJ |
| description | Nowadays, there is an increasing interest in Point-of-care (POC) devices for the noninvasive glucose assessment. Despite the recent progress in glucose self-monitoring, commercially available devices still use invasive samples such as blood or interstitial fluids, and they are not equipment-free and affordable for the whole population. Here, we report a fully integrated strip test for the semi-quantitative detection of glucose in whole saliva. The colorimetric mechanism consists of an enzyme-mediated reshaping of multibranched gold nanoparticles (MGNPs) into nanospheres with an associated plasmonic shift and consequent blue-to-red color change, clearly detectable in less than 10 min. |
| first_indexed | 2024-03-10T03:28:39Z |
| format | Article |
| id | doaj.art-12b7261983e346fc8587c9f926956c8d |
| institution | Directory Open Access Journal |
| issn | 2079-4991 |
| language | English |
| last_indexed | 2024-03-10T03:28:39Z |
| publishDate | 2021-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nanomaterials |
| spelling | doaj.art-12b7261983e346fc8587c9f926956c8d2023-11-23T12:01:34ZengMDPI AGNanomaterials2079-49912021-12-0112110510.3390/nano12010105Nanoplasmonic Strip Test for Salivary Glucose MonitoringHelena Torné-Morató0Paolo Donati1Pier Paolo Pompa2Nanobiointeractions & Nanodiagnostics, Istituto Italiano di Tecnologia (IIT), via Morego, 30-16163 Genova, ItalyNanobiointeractions & Nanodiagnostics, Istituto Italiano di Tecnologia (IIT), via Morego, 30-16163 Genova, ItalyNanobiointeractions & Nanodiagnostics, Istituto Italiano di Tecnologia (IIT), via Morego, 30-16163 Genova, ItalyNowadays, there is an increasing interest in Point-of-care (POC) devices for the noninvasive glucose assessment. Despite the recent progress in glucose self-monitoring, commercially available devices still use invasive samples such as blood or interstitial fluids, and they are not equipment-free and affordable for the whole population. Here, we report a fully integrated strip test for the semi-quantitative detection of glucose in whole saliva. The colorimetric mechanism consists of an enzyme-mediated reshaping of multibranched gold nanoparticles (MGNPs) into nanospheres with an associated plasmonic shift and consequent blue-to-red color change, clearly detectable in less than 10 min.https://www.mdpi.com/2079-4991/12/1/105colorimetric sensorgold nanoparticlesplasmonicshyperglycemiapoint-of-care |
| spellingShingle | Helena Torné-Morató Paolo Donati Pier Paolo Pompa Nanoplasmonic Strip Test for Salivary Glucose Monitoring Nanomaterials colorimetric sensor gold nanoparticles plasmonics hyperglycemia point-of-care |
| title | Nanoplasmonic Strip Test for Salivary Glucose Monitoring |
| title_full | Nanoplasmonic Strip Test for Salivary Glucose Monitoring |
| title_fullStr | Nanoplasmonic Strip Test for Salivary Glucose Monitoring |
| title_full_unstemmed | Nanoplasmonic Strip Test for Salivary Glucose Monitoring |
| title_short | Nanoplasmonic Strip Test for Salivary Glucose Monitoring |
| title_sort | nanoplasmonic strip test for salivary glucose monitoring |
| topic | colorimetric sensor gold nanoparticles plasmonics hyperglycemia point-of-care |
| url | https://www.mdpi.com/2079-4991/12/1/105 |
| work_keys_str_mv | AT helenatornemorato nanoplasmonicstriptestforsalivaryglucosemonitoring AT paolodonati nanoplasmonicstriptestforsalivaryglucosemonitoring AT pierpaolopompa nanoplasmonicstriptestforsalivaryglucosemonitoring |