Adrenoleukodystrophy/Adrenomyeloneuropathy and Neurogenic Bladder Dysfunction. A Review

One of the conditions associated with adrenoleukodystrophy (ALD) / adrenomyeloneuropathy (AMN) is neurogenic lower urinary tract dysfunction (LUTD). A thorough examination of patients with ALD/AMN in most cases can reveal overactive bladder (OAB), which often remains undiagnosed because its clinical...

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Main Authors: Khudyakova, N.V., Pchelin, I.Yu., Shishkin, A.N., Soloviev, O.V., Smirnov, V.V.
Format: Article
Language:English
Published: Scientia Publishing House 2023-10-01
Series:Juvenis Scientia
Subjects:
Online Access:https://jscientia.org/index.php/js/user/setLocale/en_US?source=/index.php/js/article/view/204?utm_source=doi
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author Khudyakova, N.V.
Pchelin, I.Yu.
Shishkin, A.N.
Soloviev, O.V.
Smirnov, V.V.
author_facet Khudyakova, N.V.
Pchelin, I.Yu.
Shishkin, A.N.
Soloviev, O.V.
Smirnov, V.V.
author_sort Khudyakova, N.V.
collection DOAJ
description One of the conditions associated with adrenoleukodystrophy (ALD) / adrenomyeloneuropathy (AMN) is neurogenic lower urinary tract dysfunction (LUTD). A thorough examination of patients with ALD/AMN in most cases can reveal overactive bladder (OAB), which often remains undiagnosed because its clinical manifestations are underestimated against the background of numerous neurologic symptoms. In addition, in some cases, urologic symptomatology is the first sign of ALD/AMN that prompts the urologist to consider further evaluation of the patient. In this case, the urologist can play a significant role in the patient’s life, as timely diagnosis and treatment of ALD/AMN improve disease outcomes and reduce the likelihood of complications of ALD/AMN-associated conditions. To date, there are few studies devoted to the understanding of LUTD in ALD/AMN. In this article, we reviewed the current literature on OAB in patients with ALD/AMN.
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spelling doaj.art-12b80934d2ff47daac0fcad8bcc628012023-10-30T06:56:58ZengScientia Publishing HouseJuvenis Scientia2414-37822414-37902023-10-0195203010.32415/jscientia_2023_9_5_20-3010.32415/jscientia_2023_9_5_20-30Adrenoleukodystrophy/Adrenomyeloneuropathy and Neurogenic Bladder Dysfunction. A ReviewKhudyakova, N.V.0Pchelin, I.Yu.1Shishkin, A.N.2Soloviev, O.V.3Smirnov, V.V.4Saint Petersburg State UniversitySaint Petersburg State UniversitySaint Petersburg State UniversitySaint Petersburg State UniversitySaint Petersburg State Pediatric Medical UniversityOne of the conditions associated with adrenoleukodystrophy (ALD) / adrenomyeloneuropathy (AMN) is neurogenic lower urinary tract dysfunction (LUTD). A thorough examination of patients with ALD/AMN in most cases can reveal overactive bladder (OAB), which often remains undiagnosed because its clinical manifestations are underestimated against the background of numerous neurologic symptoms. In addition, in some cases, urologic symptomatology is the first sign of ALD/AMN that prompts the urologist to consider further evaluation of the patient. In this case, the urologist can play a significant role in the patient’s life, as timely diagnosis and treatment of ALD/AMN improve disease outcomes and reduce the likelihood of complications of ALD/AMN-associated conditions. To date, there are few studies devoted to the understanding of LUTD in ALD/AMN. In this article, we reviewed the current literature on OAB in patients with ALD/AMN.https://jscientia.org/index.php/js/user/setLocale/en_US?source=/index.php/js/article/view/204?utm_source=doiadrenoleukodystrophyadrenomyeloneuropathyneurogenic bladder dysfunction
spellingShingle Khudyakova, N.V.
Pchelin, I.Yu.
Shishkin, A.N.
Soloviev, O.V.
Smirnov, V.V.
Adrenoleukodystrophy/Adrenomyeloneuropathy and Neurogenic Bladder Dysfunction. A Review
Juvenis Scientia
adrenoleukodystrophy
adrenomyeloneuropathy
neurogenic bladder dysfunction
title Adrenoleukodystrophy/Adrenomyeloneuropathy and Neurogenic Bladder Dysfunction. A Review
title_full Adrenoleukodystrophy/Adrenomyeloneuropathy and Neurogenic Bladder Dysfunction. A Review
title_fullStr Adrenoleukodystrophy/Adrenomyeloneuropathy and Neurogenic Bladder Dysfunction. A Review
title_full_unstemmed Adrenoleukodystrophy/Adrenomyeloneuropathy and Neurogenic Bladder Dysfunction. A Review
title_short Adrenoleukodystrophy/Adrenomyeloneuropathy and Neurogenic Bladder Dysfunction. A Review
title_sort adrenoleukodystrophy adrenomyeloneuropathy and neurogenic bladder dysfunction a review
topic adrenoleukodystrophy
adrenomyeloneuropathy
neurogenic bladder dysfunction
url https://jscientia.org/index.php/js/user/setLocale/en_US?source=/index.php/js/article/view/204?utm_source=doi
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AT pcheliniyu adrenoleukodystrophyadrenomyeloneuropathyandneurogenicbladderdysfunctionareview
AT shishkinan adrenoleukodystrophyadrenomyeloneuropathyandneurogenicbladderdysfunctionareview
AT solovievov adrenoleukodystrophyadrenomyeloneuropathyandneurogenicbladderdysfunctionareview
AT smirnovvv adrenoleukodystrophyadrenomyeloneuropathyandneurogenicbladderdysfunctionareview