Modified eQTL and Somatic DNA Segment Alterations in Esophageal Squamous Cell Carcinoma for Genes Related to Immunity, DNA Repair, and Inflammation

Modified eQTL and Somatic DNA Segment Alterations in Esophageal Squamous Cell Carcinoma for Genes Related to Immunity, DNA Repair, and Inflammation

We integrated ESCC expression and GWAS genotyping, to investigate eQTL and somatic DNA segment alterations, including somatic copy number alteration, allelic imbalance (AI), and loss of heterozygosity (LOH) in ESCC. First, in eQTL analysis, we used a classical approach based on genotype data from GW...

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Bibliographic Details
Main Authors: Howard H. Yang, Huaitian Liu, Nan Hu, Hua Su, Chaoyu Wang, Carol Giffen, Alisa M. Goldstein, Philip R. Taylor, Maxwell P. Lee
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Cancers
Subjects:
ESCC
eQTL
SNP
DNA segment alterations
Online Access:https://www.mdpi.com/2072-6694/14/7/1629

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