A cooperative interaction between nontranslated RNA sequences and NS5A protein promotes in vivo fitness of a chimeric hepatitis C/GB virus B.
GB virus B (GBV-B) is closely related to hepatitis C virus (HCV), infects small non-human primates, and is thus a valuable surrogate for studying HCV. Despite significant differences, the 5' nontranslated RNAs (NTRs) of these viruses fold into four similar structured domains (I-IV), with domain...
Main Authors: | Lucile Warter, Lisette Cohen, Yann Benureau, Deborah Chavez, Yan Yang, Francis Bodola, Stanley M Lemon, Cinzia Traboni, Robert E Lanford, Annette Martin |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2009-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC2635954?pdf=render |
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