Development of Er<sup>3+</sup>, Yb<sup>3+</sup> Co-Doped Y<sub>2</sub>O<sub>3</sub> NPs According to Yb<sup>3+</sup> Concentration by LP–PLA Method: Potential Further Biosensor
As diagnostic biosensors for analyzing fluids from the human body, the development of inorganic NPs is of increasing concern. For one, nanoceramic phosphors have been studied to meet the increasing requirements for biological, imaging, and diagnostic applications. In this study, Y<sub>2</su...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2021-05-01
|
| Series: | Biosensors |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2079-6374/11/5/150 |
| _version_ | 1827692824912461824 |
|---|---|
| author | Cheol-Woo Park Dong-Jun Park |
| author_facet | Cheol-Woo Park Dong-Jun Park |
| author_sort | Cheol-Woo Park |
| collection | DOAJ |
| description | As diagnostic biosensors for analyzing fluids from the human body, the development of inorganic NPs is of increasing concern. For one, nanoceramic phosphors have been studied to meet the increasing requirements for biological, imaging, and diagnostic applications. In this study, Y<sub>2</sub>O<sub>3</sub> NPs co-doped with trivalent rare earths (erbium and ytterbium) were obtained using a liquid phase–pulsed laser ablation (LP–PLA) method after getting high density Er, Yb:Y<sub>2</sub>O<sub>3</sub> ceramic targets by Spark plasma sintering (SPS). Most NPs are under 50 nm in diameter and show high crystallinity of cubic Y<sub>2</sub>O<sub>3</sub> structure, containing (222), (440), and (332) planes via HR–TEM. Excitation under a 980 nm laser to a nanoparticle solution showed 525 and 565 nm green, and 660 nm red emissions. The green emission intensity increased and decreased with increasing Yb<sup>3+</sup> additive concentration, when the red spectrum continuously strengthened. Utilizing this study’s outcome, we suggest developing technology to mark invisible biomolecules dissolved in a solvent using UC luminescence of Er<sup>3+</sup>, Yb<sup>3+</sup> co-doped Y<sub>2</sub>O<sub>3</sub> NPs by LP–PLA. The LP–PLA method has a potential ability for the fabrication of UC NPs for biosensors with uniform size distribution by laser parameters. |
| first_indexed | 2024-03-10T11:30:21Z |
| format | Article |
| id | doaj.art-12bb50e00b7b4659a467834c00485752 |
| institution | Directory Open Access Journal |
| issn | 2079-6374 |
| language | English |
| last_indexed | 2024-03-10T11:30:21Z |
| publishDate | 2021-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biosensors |
| spelling | doaj.art-12bb50e00b7b4659a467834c004857522023-11-21T19:14:47ZengMDPI AGBiosensors2079-63742021-05-0111515010.3390/bios11050150Development of Er<sup>3+</sup>, Yb<sup>3+</sup> Co-Doped Y<sub>2</sub>O<sub>3</sub> NPs According to Yb<sup>3+</sup> Concentration by LP–PLA Method: Potential Further BiosensorCheol-Woo Park0Dong-Jun Park1College of Engineering, San Diego State University, 5500 Campanile Drive, San Diego, CA 92182, USADepartment of Surgery, University of California San Diego 212, Dickinson Street, MC 8236 CTF B R310, San Diego, CA 92103, USAAs diagnostic biosensors for analyzing fluids from the human body, the development of inorganic NPs is of increasing concern. For one, nanoceramic phosphors have been studied to meet the increasing requirements for biological, imaging, and diagnostic applications. In this study, Y<sub>2</sub>O<sub>3</sub> NPs co-doped with trivalent rare earths (erbium and ytterbium) were obtained using a liquid phase–pulsed laser ablation (LP–PLA) method after getting high density Er, Yb:Y<sub>2</sub>O<sub>3</sub> ceramic targets by Spark plasma sintering (SPS). Most NPs are under 50 nm in diameter and show high crystallinity of cubic Y<sub>2</sub>O<sub>3</sub> structure, containing (222), (440), and (332) planes via HR–TEM. Excitation under a 980 nm laser to a nanoparticle solution showed 525 and 565 nm green, and 660 nm red emissions. The green emission intensity increased and decreased with increasing Yb<sup>3+</sup> additive concentration, when the red spectrum continuously strengthened. Utilizing this study’s outcome, we suggest developing technology to mark invisible biomolecules dissolved in a solvent using UC luminescence of Er<sup>3+</sup>, Yb<sup>3+</sup> co-doped Y<sub>2</sub>O<sub>3</sub> NPs by LP–PLA. The LP–PLA method has a potential ability for the fabrication of UC NPs for biosensors with uniform size distribution by laser parameters.https://www.mdpi.com/2079-6374/11/5/150diagnostic materialY<sub>2</sub>O<sub>3</sub>:Er<sup>3+</sup>Yb<sup>3+</sup>nano ceramic particlesup-conversion luminescenceliquid phase–pulsed laser ablation |
| spellingShingle | Cheol-Woo Park Dong-Jun Park Development of Er<sup>3+</sup>, Yb<sup>3+</sup> Co-Doped Y<sub>2</sub>O<sub>3</sub> NPs According to Yb<sup>3+</sup> Concentration by LP–PLA Method: Potential Further Biosensor Biosensors diagnostic material Y<sub>2</sub>O<sub>3</sub>:Er<sup>3+</sup> Yb<sup>3+</sup> nano ceramic particles up-conversion luminescence liquid phase–pulsed laser ablation |
| title | Development of Er<sup>3+</sup>, Yb<sup>3+</sup> Co-Doped Y<sub>2</sub>O<sub>3</sub> NPs According to Yb<sup>3+</sup> Concentration by LP–PLA Method: Potential Further Biosensor |
| title_full | Development of Er<sup>3+</sup>, Yb<sup>3+</sup> Co-Doped Y<sub>2</sub>O<sub>3</sub> NPs According to Yb<sup>3+</sup> Concentration by LP–PLA Method: Potential Further Biosensor |
| title_fullStr | Development of Er<sup>3+</sup>, Yb<sup>3+</sup> Co-Doped Y<sub>2</sub>O<sub>3</sub> NPs According to Yb<sup>3+</sup> Concentration by LP–PLA Method: Potential Further Biosensor |
| title_full_unstemmed | Development of Er<sup>3+</sup>, Yb<sup>3+</sup> Co-Doped Y<sub>2</sub>O<sub>3</sub> NPs According to Yb<sup>3+</sup> Concentration by LP–PLA Method: Potential Further Biosensor |
| title_short | Development of Er<sup>3+</sup>, Yb<sup>3+</sup> Co-Doped Y<sub>2</sub>O<sub>3</sub> NPs According to Yb<sup>3+</sup> Concentration by LP–PLA Method: Potential Further Biosensor |
| title_sort | development of er sup 3 sup yb sup 3 sup co doped y sub 2 sub o sub 3 sub nps according to yb sup 3 sup concentration by lp pla method potential further biosensor |
| topic | diagnostic material Y<sub>2</sub>O<sub>3</sub>:Er<sup>3+</sup> Yb<sup>3+</sup> nano ceramic particles up-conversion luminescence liquid phase–pulsed laser ablation |
| url | https://www.mdpi.com/2079-6374/11/5/150 |
| work_keys_str_mv | AT cheolwoopark developmentofersup3supybsup3supcodopedysub2subosub3subnpsaccordingtoybsup3supconcentrationbylpplamethodpotentialfurtherbiosensor AT dongjunpark developmentofersup3supybsup3supcodopedysub2subosub3subnpsaccordingtoybsup3supconcentrationbylpplamethodpotentialfurtherbiosensor |