Pancytopenia associated with clonazepam
<p>Abstract</p> <p>We report a case of a 48-year-old Chinese female with end-stage renal disease and chronic anemia on hemodialysis. Clonazepam was prescribed for myoclonus disorder two weeks prior to her hospitalization. Subsequently, she was hospitalized for neutropenic fever wit...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2010-07-01
|
| Series: | Journal of Hematology & Oncology |
| Online Access: | http://www.jhoonline.org/content/3/1/24 |
| _version_ | 1818520450245853184 |
|---|---|
| author | Hsueh Chung-Tsen Liao Yu-Min Bautista-Quach Marnelli A |
| author_facet | Hsueh Chung-Tsen Liao Yu-Min Bautista-Quach Marnelli A |
| author_sort | Hsueh Chung-Tsen |
| collection | DOAJ |
| description | <p>Abstract</p> <p>We report a case of a 48-year-old Chinese female with end-stage renal disease and chronic anemia on hemodialysis. Clonazepam was prescribed for myoclonus disorder two weeks prior to her hospitalization. Subsequently, she was hospitalized for neutropenic fever with thrombocytopenia and worsening anemia. Bone marrow examination demonstrated a markedly hypocellular marrow (10-20% total cellularity). Clonazepam was discontinued, with gradual improvement of thrombocytopenia, and neutropenia in 1-2 weeks. To our knowledge, this is the first reported case of pancytopenia associated with clonazepam. We recommend patients taking clonazepam to be monitored with regular complete blood count to check for clinically significant pancytopenia or thrombocytopenia.</p> |
| first_indexed | 2024-12-11T01:37:42Z |
| format | Article |
| id | doaj.art-12bc11c224514337a6a11d53b11e733b |
| institution | Directory Open Access Journal |
| issn | 1756-8722 |
| language | English |
| last_indexed | 2024-12-11T01:37:42Z |
| publishDate | 2010-07-01 |
| publisher | BMC |
| record_format | Article |
| series | Journal of Hematology & Oncology |
| spelling | doaj.art-12bc11c224514337a6a11d53b11e733b2022-12-22T01:25:08ZengBMCJournal of Hematology & Oncology1756-87222010-07-01312410.1186/1756-8722-3-24Pancytopenia associated with clonazepamHsueh Chung-TsenLiao Yu-MinBautista-Quach Marnelli A<p>Abstract</p> <p>We report a case of a 48-year-old Chinese female with end-stage renal disease and chronic anemia on hemodialysis. Clonazepam was prescribed for myoclonus disorder two weeks prior to her hospitalization. Subsequently, she was hospitalized for neutropenic fever with thrombocytopenia and worsening anemia. Bone marrow examination demonstrated a markedly hypocellular marrow (10-20% total cellularity). Clonazepam was discontinued, with gradual improvement of thrombocytopenia, and neutropenia in 1-2 weeks. To our knowledge, this is the first reported case of pancytopenia associated with clonazepam. We recommend patients taking clonazepam to be monitored with regular complete blood count to check for clinically significant pancytopenia or thrombocytopenia.</p>http://www.jhoonline.org/content/3/1/24 |
| spellingShingle | Hsueh Chung-Tsen Liao Yu-Min Bautista-Quach Marnelli A Pancytopenia associated with clonazepam Journal of Hematology & Oncology |
| title | Pancytopenia associated with clonazepam |
| title_full | Pancytopenia associated with clonazepam |
| title_fullStr | Pancytopenia associated with clonazepam |
| title_full_unstemmed | Pancytopenia associated with clonazepam |
| title_short | Pancytopenia associated with clonazepam |
| title_sort | pancytopenia associated with clonazepam |
| url | http://www.jhoonline.org/content/3/1/24 |
| work_keys_str_mv | AT hsuehchungtsen pancytopeniaassociatedwithclonazepam AT liaoyumin pancytopeniaassociatedwithclonazepam AT bautistaquachmarnellia pancytopeniaassociatedwithclonazepam |