Prevention and treatment of cancers by tumor antigen-expressing Staphylococcus epidermidis
ABSTRACTIn a recent paper in Science, Chen et al. reported the genetic engineering of S. epidermidis expressing tumor cross-reactive antigens that trigger T cell responses and exhibit anticancer effects after topical administration. Here we discuss direct local effects and indirect systemic effects...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis Group
2023-12-01
|
| Series: | OncoImmunology |
| Subjects: | |
| Online Access: | https://www.tandfonline.com/doi/10.1080/2162402X.2023.2212547 |
| _version_ | 1797367103395725312 |
|---|---|
| author | Oliver Kepp Laurence Zitvogel Guido Kroemer |
| author_facet | Oliver Kepp Laurence Zitvogel Guido Kroemer |
| author_sort | Oliver Kepp |
| collection | DOAJ |
| description | ABSTRACTIn a recent paper in Science, Chen et al. reported the genetic engineering of S. epidermidis expressing tumor cross-reactive antigens that trigger T cell responses and exhibit anticancer effects after topical administration. Here we discuss direct local effects and indirect systemic effects of exposure to engineered S. epidermidis strains. |
| first_indexed | 2024-03-08T17:12:30Z |
| format | Article |
| id | doaj.art-12bd6bfc2b384fea8b867f10392df495 |
| institution | Directory Open Access Journal |
| issn | 2162-402X |
| language | English |
| last_indexed | 2024-03-08T17:12:30Z |
| publishDate | 2023-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | OncoImmunology |
| spelling | doaj.art-12bd6bfc2b384fea8b867f10392df4952024-01-03T19:25:36ZengTaylor & Francis GroupOncoImmunology2162-402X2023-12-0112110.1080/2162402X.2023.2212547Prevention and treatment of cancers by tumor antigen-expressing Staphylococcus epidermidisOliver Kepp0Laurence Zitvogel1Guido Kroemer2Metabolomics and Cell Biology Platforms, Gustave Roussy Cancer Center, Université Paris Saclay, Villejuif, FranceGustave Roussy Comprehensive Cancer Institute, Villejuif, FranceMetabolomics and Cell Biology Platforms, Gustave Roussy Cancer Center, Université Paris Saclay, Villejuif, FranceABSTRACTIn a recent paper in Science, Chen et al. reported the genetic engineering of S. epidermidis expressing tumor cross-reactive antigens that trigger T cell responses and exhibit anticancer effects after topical administration. Here we discuss direct local effects and indirect systemic effects of exposure to engineered S. epidermidis strains.https://www.tandfonline.com/doi/10.1080/2162402X.2023.2212547ImmunotherapyMicrobiomeImmunity |
| spellingShingle | Oliver Kepp Laurence Zitvogel Guido Kroemer Prevention and treatment of cancers by tumor antigen-expressing Staphylococcus epidermidis OncoImmunology Immunotherapy Microbiome Immunity |
| title | Prevention and treatment of cancers by tumor antigen-expressing Staphylococcus epidermidis |
| title_full | Prevention and treatment of cancers by tumor antigen-expressing Staphylococcus epidermidis |
| title_fullStr | Prevention and treatment of cancers by tumor antigen-expressing Staphylococcus epidermidis |
| title_full_unstemmed | Prevention and treatment of cancers by tumor antigen-expressing Staphylococcus epidermidis |
| title_short | Prevention and treatment of cancers by tumor antigen-expressing Staphylococcus epidermidis |
| title_sort | prevention and treatment of cancers by tumor antigen expressing staphylococcus epidermidis |
| topic | Immunotherapy Microbiome Immunity |
| url | https://www.tandfonline.com/doi/10.1080/2162402X.2023.2212547 |
| work_keys_str_mv | AT oliverkepp preventionandtreatmentofcancersbytumorantigenexpressingstaphylococcusepidermidis AT laurencezitvogel preventionandtreatmentofcancersbytumorantigenexpressingstaphylococcusepidermidis AT guidokroemer preventionandtreatmentofcancersbytumorantigenexpressingstaphylococcusepidermidis |