Association Between BDNF Gene Variant Rs6265 and the Severity of Depression in Antidepressant Treatment-Free Depressed Patients

Association Between BDNF Gene Variant Rs6265 and the Severity of Depression in Antidepressant Treatment-Free Depressed Patients

BackgroundBrain-derived neurotrophic factor (BDNF) plays an important role in neuronal plasticity, and its dysregulation has been associated with the pathogenesis of mood and anxiety disorders. Prolactin (PRL) is a pituitary hormone which is also produced as a cytokine by immune cells and could be a...

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Bibliographic Details
Main Authors: Innokentiy S. Losenkov, Nathaniël J. V. Mulder, Lyudmila A. Levchuk, Natalya M. Vyalova, Anton J. M. Loonen, Fokko J. Bosker, German G. Simutkin, Anastasiia S. Boiko, Nikolay A. Bokhan, Bob Wilffert, Eelko Hak, Amand F. Schmidt, Svetlana A. Ivanova
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Psychiatry
Subjects:
major depressive disorder
prolactin
brain derived neurotrophic factor
blood levels
genotypes
rs6265
Online Access:https://www.frontiersin.org/article/10.3389/fpsyt.2020.00038/full

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