Effectiveness of Ginseng, Rutin and Moringa for the Treatment of Erectile Dysfunction: A Systematic Review
<b>Introduction</b>, The aim of this systematic review was to evaluate the current evidence for the effectiveness of ginseng, Rutin and Moringa for treating erectile dysfunction. <b>Methods</b>, A broad search of the Scopus, PubMed, Cochrane and Web of Science databases was p...
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| Format: | Article |
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MDPI AG
2022-04-01
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| Online Access: | https://www.mdpi.com/2673-4397/2/2/9 |
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| author | Giacomo Rebez Paolo Capogrosso Luca Boeri Michele Rizzo Carlos Miacola Tommaso Cai Fabrizio Palumbo Ilaria Ortensi Carlo Ceruti Stefano Lauretti Marco Bitelli Giovanni Liguori Danilo Di Trapani Alessandro Palmieri on behalf of the Italian Society of Andrology |
| author_facet | Giacomo Rebez Paolo Capogrosso Luca Boeri Michele Rizzo Carlos Miacola Tommaso Cai Fabrizio Palumbo Ilaria Ortensi Carlo Ceruti Stefano Lauretti Marco Bitelli Giovanni Liguori Danilo Di Trapani Alessandro Palmieri on behalf of the Italian Society of Andrology |
| author_sort | Giacomo Rebez |
| collection | DOAJ |
| description | <b>Introduction</b>, The aim of this systematic review was to evaluate the current evidence for the effectiveness of ginseng, Rutin and Moringa for treating erectile dysfunction. <b>Methods</b>, A broad search of the Scopus, PubMed, Cochrane and Web of Science databases was performed in complicance with the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines. The following criteria were required for articles to be included in the review: English language; observational studies (cohort studies, case control/comparative studies, single-arm studies); randomized controlled trials; non-randomized comparative studies; case series; number of participants: ≥5 for case series or ≥5 patients per group for comparative studies. The Cochrane risk of bias (RoB) assessment tool for RCTs was used to assess the risk of bias of included studies. <b>Results</b>, Seven full-text articles were included in this review. All studies were randomized controlled trials. No studies on Rutin and Moringa alone matched the inclusion criteria. The methodological quality of the RCTs was variable. In all studies, the group treated with ginseng reported an improvement of erectile function (EF) compared to the control groups. IIEF and IIEF-5 were used to evaluate erectile function in six studies and in four of them, the improvement of the scores in the group treated with ginseng over the control group reached the statistical significance. <b>Conclusion</b>, This review suggests a positive effect of ginseng on EF in men. The association of ginseng along with other nutritional components with potential beneficial effects on ED appears promising and deserves further investigation in large randomized controlled trials. |
| first_indexed | 2024-03-09T22:17:54Z |
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| institution | Directory Open Access Journal |
| issn | 2673-4397 |
| language | English |
| last_indexed | 2024-03-09T22:17:54Z |
| publishDate | 2022-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Uro |
| spelling | doaj.art-12be5b394ab54406bd0ceed4f50519b82023-11-23T19:19:47ZengMDPI AGUro2673-43972022-04-0122657310.3390/uro2020009Effectiveness of Ginseng, Rutin and Moringa for the Treatment of Erectile Dysfunction: A Systematic ReviewGiacomo Rebez0Paolo Capogrosso1Luca Boeri2Michele Rizzo3Carlos Miacola4Tommaso Cai5Fabrizio Palumbo6Ilaria Ortensi7Carlo Ceruti8Stefano Lauretti9Marco Bitelli10Giovanni Liguori11Danilo Di Trapani12Alessandro Palmieri13on behalf of the Italian Society of Andrology14Department of Urology, Cattinara Hospital, ASUGI, University of Trieste, 34127 Trieste, ItalyDepartment of Urology and Andrology, Ospedale di Circolo and Macchi Foundation, 21100 Varese, ItalyDepartment of Urology, Foundation IRCCS Ca’ Granda—Ospedale Maggiore Policlinico, University of Milan, 20122 Milan, ItalyDepartment of Urology, Cattinara Hospital, ASUGI, University of Trieste, 34127 Trieste, ItalyDepartment of Emergency and Organ Transplantation, Urology, Andrology and Kidney Transplantation Unit, University of Bari, 70121 Bari, ItalyDepartment of Urology, Santa Chiara Regional Hospital, 38123 Trento, ItalyDepartment of Urology, Di Venere Hospital, 70131 Bari, ItalyLaboratory Altamedica, 00198 Rome, ItalyUrology Clinic, Città della Salute e della Scienza, University of Turin, 10124 Turin, ItalyServizio di Andrologia Chirurgica e Medicina Rigenerativa, Santa Caterina della Rosa Clinic ASL ROMA 2, 00176 Rome, ItalyServizio di Andrologia Chirurgica, UOSD Urologia, Ospedale S. Sebastiano Martire, 00044 Rome, ItalyDepartment of Urology, Cattinara Hospital, ASUGI, University of Trieste, 34127 Trieste, ItalyUrologist and Andrologist, 90143 Palermo, ItalyDepartment of Urology, AOU Federico II, University Hospital, 80137 Naples, ItalyThe Italian Society of Andrology, Via Torino 135, 00135 Rome, Italy<b>Introduction</b>, The aim of this systematic review was to evaluate the current evidence for the effectiveness of ginseng, Rutin and Moringa for treating erectile dysfunction. <b>Methods</b>, A broad search of the Scopus, PubMed, Cochrane and Web of Science databases was performed in complicance with the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines. The following criteria were required for articles to be included in the review: English language; observational studies (cohort studies, case control/comparative studies, single-arm studies); randomized controlled trials; non-randomized comparative studies; case series; number of participants: ≥5 for case series or ≥5 patients per group for comparative studies. The Cochrane risk of bias (RoB) assessment tool for RCTs was used to assess the risk of bias of included studies. <b>Results</b>, Seven full-text articles were included in this review. All studies were randomized controlled trials. No studies on Rutin and Moringa alone matched the inclusion criteria. The methodological quality of the RCTs was variable. In all studies, the group treated with ginseng reported an improvement of erectile function (EF) compared to the control groups. IIEF and IIEF-5 were used to evaluate erectile function in six studies and in four of them, the improvement of the scores in the group treated with ginseng over the control group reached the statistical significance. <b>Conclusion</b>, This review suggests a positive effect of ginseng on EF in men. The association of ginseng along with other nutritional components with potential beneficial effects on ED appears promising and deserves further investigation in large randomized controlled trials.https://www.mdpi.com/2673-4397/2/2/9erectile functionginsengsystematic reviewerectile dysfunction |
| spellingShingle | Giacomo Rebez Paolo Capogrosso Luca Boeri Michele Rizzo Carlos Miacola Tommaso Cai Fabrizio Palumbo Ilaria Ortensi Carlo Ceruti Stefano Lauretti Marco Bitelli Giovanni Liguori Danilo Di Trapani Alessandro Palmieri on behalf of the Italian Society of Andrology Effectiveness of Ginseng, Rutin and Moringa for the Treatment of Erectile Dysfunction: A Systematic Review Uro erectile function ginseng systematic review erectile dysfunction |
| title | Effectiveness of Ginseng, Rutin and Moringa for the Treatment of Erectile Dysfunction: A Systematic Review |
| title_full | Effectiveness of Ginseng, Rutin and Moringa for the Treatment of Erectile Dysfunction: A Systematic Review |
| title_fullStr | Effectiveness of Ginseng, Rutin and Moringa for the Treatment of Erectile Dysfunction: A Systematic Review |
| title_full_unstemmed | Effectiveness of Ginseng, Rutin and Moringa for the Treatment of Erectile Dysfunction: A Systematic Review |
| title_short | Effectiveness of Ginseng, Rutin and Moringa for the Treatment of Erectile Dysfunction: A Systematic Review |
| title_sort | effectiveness of ginseng rutin and moringa for the treatment of erectile dysfunction a systematic review |
| topic | erectile function ginseng systematic review erectile dysfunction |
| url | https://www.mdpi.com/2673-4397/2/2/9 |
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