Bilateral Choanal Atresia and Endoscopic Surgery: A Chance for CHARGE Patients
Bilateral choanal atresia (CA) is a rare congenital malformation frequently associated with other anomalies. CHARGE association is closely linked to bilateral CA. The aim of this study was to describe the outcomes of the endoscopic repair in bilateral CA, and to assess the role of postoperative nasa...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-06-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/10/13/2951 |
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| author | Maria Baldovin Diego Cazzador Claudia Zanotti Giuliana Frasson Athanasios Saratziotis Fabio Pagella Stefano Pelucchi Enzo Emanuelli |
| author_facet | Maria Baldovin Diego Cazzador Claudia Zanotti Giuliana Frasson Athanasios Saratziotis Fabio Pagella Stefano Pelucchi Enzo Emanuelli |
| author_sort | Maria Baldovin |
| collection | DOAJ |
| description | Bilateral choanal atresia (CA) is a rare congenital malformation frequently associated with other anomalies. CHARGE association is closely linked to bilateral CA. The aim of this study was to describe the outcomes of the endoscopic repair in bilateral CA, and to assess the role of postoperative nasal stenting in two cohorts of CHARGE-associated and non-syndromic CA. Thirty-nine children were retrospectively analyzed (16 patients had CHARGE-associated CA). The rate of postoperative neochoanal restenosis was 31.3% in the CHARGE population, and 47.8% in the non-syndromic CA cohort. Data on postoperative synechiae and granulation tissue formation, need for endonasal toilette and dilation procedures, and number of procedures per patient were presented. Stent positioning led to a higher number of postoperative dilation procedures per patient in the non-syndromic cohort (<i>p</i> = 0.018), and to a higher rate of restenosis both in the CHARGE-associated, and non-syndromic CA populations. Children with CHARGE-associated and non-syndromic bilateral CA benefitted from endonasal endoscopic CA correction. The postoperative application of an endonasal stent should be carefully evaluated. |
| first_indexed | 2024-03-10T09:54:26Z |
| format | Article |
| id | doaj.art-12c478be5b354790a57204273650a95e |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-10T09:54:26Z |
| publishDate | 2021-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-12c478be5b354790a57204273650a95e2023-11-22T02:26:15ZengMDPI AGJournal of Clinical Medicine2077-03832021-06-011013295110.3390/jcm10132951Bilateral Choanal Atresia and Endoscopic Surgery: A Chance for CHARGE PatientsMaria Baldovin0Diego Cazzador1Claudia Zanotti2Giuliana Frasson3Athanasios Saratziotis4Fabio Pagella5Stefano Pelucchi6Enzo Emanuelli7Department of Neurosciences, Section of Otorhinolaryngology, University of Padova, 35128 Padova, ItalyDepartment of Neurosciences, Section of Otorhinolaryngology, University of Padova, 35128 Padova, ItalyDepartment of Neurosciences, Section of Otorhinolaryngology, University of Padova, 35128 Padova, ItalyUnit of Otorhinolaryngology, Ospedale di Cittadella, 35013 Cittadella, ItalyDepartment of Otolaryngology, Head and Neck Surgery, University Hospital of Larissa, 41110 Larissa, GreeceENT Department, I.R.C.C.S. Policlinico San Matteo-University of Pavia, 27100 Pavia, ItalyENT & Audiology Unit, Department of Neuroscience and Rehabilitation, University Hospital of Ferrara, 44124 Ferrara, ItalyDepartment of Neurosciences, Section of Otorhinolaryngology, University of Padova, 35128 Padova, ItalyBilateral choanal atresia (CA) is a rare congenital malformation frequently associated with other anomalies. CHARGE association is closely linked to bilateral CA. The aim of this study was to describe the outcomes of the endoscopic repair in bilateral CA, and to assess the role of postoperative nasal stenting in two cohorts of CHARGE-associated and non-syndromic CA. Thirty-nine children were retrospectively analyzed (16 patients had CHARGE-associated CA). The rate of postoperative neochoanal restenosis was 31.3% in the CHARGE population, and 47.8% in the non-syndromic CA cohort. Data on postoperative synechiae and granulation tissue formation, need for endonasal toilette and dilation procedures, and number of procedures per patient were presented. Stent positioning led to a higher number of postoperative dilation procedures per patient in the non-syndromic cohort (<i>p</i> = 0.018), and to a higher rate of restenosis both in the CHARGE-associated, and non-syndromic CA populations. Children with CHARGE-associated and non-syndromic bilateral CA benefitted from endonasal endoscopic CA correction. The postoperative application of an endonasal stent should be carefully evaluated.https://www.mdpi.com/2077-0383/10/13/2951choanal atresiabilateralCHARGE associationendoscopic surgerystentpostoperative outcomes |
| spellingShingle | Maria Baldovin Diego Cazzador Claudia Zanotti Giuliana Frasson Athanasios Saratziotis Fabio Pagella Stefano Pelucchi Enzo Emanuelli Bilateral Choanal Atresia and Endoscopic Surgery: A Chance for CHARGE Patients Journal of Clinical Medicine choanal atresia bilateral CHARGE association endoscopic surgery stent postoperative outcomes |
| title | Bilateral Choanal Atresia and Endoscopic Surgery: A Chance for CHARGE Patients |
| title_full | Bilateral Choanal Atresia and Endoscopic Surgery: A Chance for CHARGE Patients |
| title_fullStr | Bilateral Choanal Atresia and Endoscopic Surgery: A Chance for CHARGE Patients |
| title_full_unstemmed | Bilateral Choanal Atresia and Endoscopic Surgery: A Chance for CHARGE Patients |
| title_short | Bilateral Choanal Atresia and Endoscopic Surgery: A Chance for CHARGE Patients |
| title_sort | bilateral choanal atresia and endoscopic surgery a chance for charge patients |
| topic | choanal atresia bilateral CHARGE association endoscopic surgery stent postoperative outcomes |
| url | https://www.mdpi.com/2077-0383/10/13/2951 |
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