Antimalarial combination therapies increase gastric ulcers through an imbalance of basic antioxidative-oxidative enzymes in male Wistar rats

Antimalarial combination therapies increase gastric ulcers through an imbalance of basic antioxidative-oxidative enzymes in male Wistar rats

Abstract Objective Antimalarials are globally used against plasmodium infections, however, information on the safety of new antimalarial combination therapies on the gastric mucosa is scarce. The aim of this study was to investigate the effects of Artesunate-Amodiaquine and Artemether-Lumefantrine o...

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Bibliographic Details
Main Authors: Muhamudu Kalange, Miriam Nansunga, Keneth Iceland Kasozi, Josephine Kasolo, Jackline Namulema, Jovile Kasande Atusiimirwe, Emanuel Tiyo Ayikobua, Fred Ssempijja, Edson Ireeta Munanura, Kevin Matama, Ibrahim Semuyaba, Gerald Zirintunda, Alfred Omachonu Okpanachi
Format: Article
Language:English
Published: BMC 2020-04-01
Series:BMC Research Notes
Subjects:
Antimalarials
Pharmacodynamics of antimalarial agents
Malaria in developing countries
Gastric ulcers
Online Access:http://link.springer.com/article/10.1186/s13104-020-05073-7

Internet

http://link.springer.com/article/10.1186/s13104-020-05073-7

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