The Simultaneous Effect of Endurance Training and Octopamine Supplementation on Octopamine and its Receptors in the Visceral Fat Tissue of Rats Treated with Deep Fried Oil (DFO)
Introduction: The role of exercise and some supplements in lipolysis has been reported, but given limited information on the simultaneous effect of endurance training (ET) and octopamine (Oct), the present study aimed to investigate the interactive effect of these two interventions on adipose tissue...
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| Format: | Article |
| Language: | English |
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Mashhad University of Medical Sciences
2022-09-01
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| Series: | Journal of Fasting and Health |
| Subjects: | |
| Online Access: | https://jnfh.mums.ac.ir/article_20969_716cb0dfd090c364586231fab1692618.pdf |
| _version_ | 1811324475468152832 |
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| author | Mahnaz Vesali Mohammad Ali Azarbayjani Maghsoud Peeri |
| author_facet | Mahnaz Vesali Mohammad Ali Azarbayjani Maghsoud Peeri |
| author_sort | Mahnaz Vesali |
| collection | DOAJ |
| description | Introduction: The role of exercise and some supplements in lipolysis has been reported, but given limited information on the simultaneous effect of endurance training (ET) and octopamine (Oct), the present study aimed to investigate the interactive effect of these two interventions on adipose tissue lipolysis with emphasis on octopamine receptors in rats treated with deep fried oil (DFO). Methods: Thirty male Wistar rats (20-18 weeks old and 280-320 g) were divided into five groups, including (1) healthy control (C), (2) DFO, (3) Oct+DFO, (4) ET+DFO and (5) DFO+Oct+ET. Aerobic training was performed for four weeks, five sessions per week with an intensity of 16-26 m / min and equivalent to 50-65% VO2max; also, 81 μmol/kg octopamine supplementation was intraperitonally injected to rats 5 days a week. Two-way analysis of variance and Bonferroni's post hoc test were used to analyze the data. Results: ET increases Octβ-R expression (P=0.02) and Oct protein concentration (P=0.001) in the visceral adipose tissue of rats exposed to DFO. Oct supplementation increases Octα-R (P=0.01) expression in the visceral adipose tissue of rats exposed to DFO. Also, ET and Oct do not have a synergistic effect on Octβ-R (P=0.91), Octα-R (P=0.65) and Oct protein concentration (P=0.16) in the visceral adipose tissue of rats exposed to DFO. Conclusion: It seems that although training and octopamine supplementation alone play a role in increasing the protein concentration of octopamine and its receptors, these two interventions do not have a synergistic effect on lipolysis by emphasizing the octopamine receptor pathway. |
| first_indexed | 2024-04-13T14:16:05Z |
| format | Article |
| id | doaj.art-12c7d7a3f44f4217b62b498e3eced67b |
| institution | Directory Open Access Journal |
| issn | 2345-2587 |
| language | English |
| last_indexed | 2024-04-13T14:16:05Z |
| publishDate | 2022-09-01 |
| publisher | Mashhad University of Medical Sciences |
| record_format | Article |
| series | Journal of Fasting and Health |
| spelling | doaj.art-12c7d7a3f44f4217b62b498e3eced67b2022-12-22T02:43:39ZengMashhad University of Medical SciencesJournal of Fasting and Health2345-25872022-09-0110323224010.22038/jnfh.2022.66872.139720969The Simultaneous Effect of Endurance Training and Octopamine Supplementation on Octopamine and its Receptors in the Visceral Fat Tissue of Rats Treated with Deep Fried Oil (DFO)Mahnaz Vesali0Mohammad Ali Azarbayjani1Maghsoud Peeri2Department of Exercise Physiology, Central Tehran Branch, Islamic Azad University, Tehran, Iran.Department of Exercise Physiology, Central Tehran Branch, Islamic Azad University, Tehran, Iran.Department of Exercise Physiology, Central Tehran Branch, Islamic Azad University, Tehran, Iran.Introduction: The role of exercise and some supplements in lipolysis has been reported, but given limited information on the simultaneous effect of endurance training (ET) and octopamine (Oct), the present study aimed to investigate the interactive effect of these two interventions on adipose tissue lipolysis with emphasis on octopamine receptors in rats treated with deep fried oil (DFO). Methods: Thirty male Wistar rats (20-18 weeks old and 280-320 g) were divided into five groups, including (1) healthy control (C), (2) DFO, (3) Oct+DFO, (4) ET+DFO and (5) DFO+Oct+ET. Aerobic training was performed for four weeks, five sessions per week with an intensity of 16-26 m / min and equivalent to 50-65% VO2max; also, 81 μmol/kg octopamine supplementation was intraperitonally injected to rats 5 days a week. Two-way analysis of variance and Bonferroni's post hoc test were used to analyze the data. Results: ET increases Octβ-R expression (P=0.02) and Oct protein concentration (P=0.001) in the visceral adipose tissue of rats exposed to DFO. Oct supplementation increases Octα-R (P=0.01) expression in the visceral adipose tissue of rats exposed to DFO. Also, ET and Oct do not have a synergistic effect on Octβ-R (P=0.91), Octα-R (P=0.65) and Oct protein concentration (P=0.16) in the visceral adipose tissue of rats exposed to DFO. Conclusion: It seems that although training and octopamine supplementation alone play a role in increasing the protein concentration of octopamine and its receptors, these two interventions do not have a synergistic effect on lipolysis by emphasizing the octopamine receptor pathway.https://jnfh.mums.ac.ir/article_20969_716cb0dfd090c364586231fab1692618.pdfendurance trainingoctopaminelipolysisintra-abdominal fatdiethigh-fat |
| spellingShingle | Mahnaz Vesali Mohammad Ali Azarbayjani Maghsoud Peeri The Simultaneous Effect of Endurance Training and Octopamine Supplementation on Octopamine and its Receptors in the Visceral Fat Tissue of Rats Treated with Deep Fried Oil (DFO) Journal of Fasting and Health endurance training octopamine lipolysis intra-abdominal fat diet high-fat |
| title | The Simultaneous Effect of Endurance Training and Octopamine Supplementation on Octopamine and its Receptors in the Visceral Fat Tissue of Rats Treated with Deep Fried Oil (DFO) |
| title_full | The Simultaneous Effect of Endurance Training and Octopamine Supplementation on Octopamine and its Receptors in the Visceral Fat Tissue of Rats Treated with Deep Fried Oil (DFO) |
| title_fullStr | The Simultaneous Effect of Endurance Training and Octopamine Supplementation on Octopamine and its Receptors in the Visceral Fat Tissue of Rats Treated with Deep Fried Oil (DFO) |
| title_full_unstemmed | The Simultaneous Effect of Endurance Training and Octopamine Supplementation on Octopamine and its Receptors in the Visceral Fat Tissue of Rats Treated with Deep Fried Oil (DFO) |
| title_short | The Simultaneous Effect of Endurance Training and Octopamine Supplementation on Octopamine and its Receptors in the Visceral Fat Tissue of Rats Treated with Deep Fried Oil (DFO) |
| title_sort | simultaneous effect of endurance training and octopamine supplementation on octopamine and its receptors in the visceral fat tissue of rats treated with deep fried oil dfo |
| topic | endurance training octopamine lipolysis intra-abdominal fat diet high-fat |
| url | https://jnfh.mums.ac.ir/article_20969_716cb0dfd090c364586231fab1692618.pdf |
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