Decomposing the Apoptosis Pathway Into Biologically Interpretable Principal Components
Principal component analysis (PCA) is one of the most common techniques in the analysis of biological data sets, but applying PCA raises 2 challenges. First, one must determine the number of significant principal components (PCs). Second, because each PC is a linear combination of genes, it rarely h...
Main Authors: | Min Wang, Steven M Kornblau, Kevin R Coombes |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2018-05-01
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Series: | Cancer Informatics |
Online Access: | https://doi.org/10.1177/1176935118771082 |
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