The function and regulation of CCAAT/enhancer binding protein ε

In recent years, studies on the structure, function, and regulation of the C/EBPε gene have become an essential topic in the field of many diseases. CCAAT/enhancer-binding protein ε (C/EBPε) is the fifth member of the transcription factor CCAAT/C/EBP family of transcription factors. It plays crucial...

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Main Authors: Shaowen Cheng, Jian Yang, Yudie Wang, Lina Xian, Zhihua Hu, Lingyun Zou
Format: Article
Language:English
Published: SAGE Publishing 2023-01-01
Series:European Journal of Inflammation
Online Access:https://doi.org/10.1177/1721727X231153322
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author Shaowen Cheng
Jian Yang
Yudie Wang
Lina Xian
Zhihua Hu
Lingyun Zou
author_facet Shaowen Cheng
Jian Yang
Yudie Wang
Lina Xian
Zhihua Hu
Lingyun Zou
author_sort Shaowen Cheng
collection DOAJ
description In recent years, studies on the structure, function, and regulation of the C/EBPε gene have become an essential topic in the field of many diseases. CCAAT/enhancer-binding protein ε (C/EBPε) is the fifth member of the transcription factor CCAAT/C/EBP family of transcription factors. It plays crucial roles in cell proliferation, differentiation, immunity, energy metabolism, and hematopoiesis. C/EBPε plays essential roles in regulating the hematopoietic system, including myeloid cell development and maturation, participation in the body’s immune responses, and prevention of infections. C/EBPε function is regulated by phosphorylation, acetylation, methylation, and other types of genes. This review related to C/EBPε structure, function and regulation provides a theoretical basis for subsequent research in this area. C/EBPε is an emerging therapeutic target and thus provides new strategies for disease prevention and control.
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spelling doaj.art-12ca4b50004a4053a6ceccd936a84b852023-01-31T14:33:58ZengSAGE PublishingEuropean Journal of Inflammation2058-73922023-01-012110.1177/1721727X231153322The function and regulation of CCAAT/enhancer binding protein εShaowen ChengJian YangYudie WangLina XianZhihua HuLingyun ZouIn recent years, studies on the structure, function, and regulation of the C/EBPε gene have become an essential topic in the field of many diseases. CCAAT/enhancer-binding protein ε (C/EBPε) is the fifth member of the transcription factor CCAAT/C/EBP family of transcription factors. It plays crucial roles in cell proliferation, differentiation, immunity, energy metabolism, and hematopoiesis. C/EBPε plays essential roles in regulating the hematopoietic system, including myeloid cell development and maturation, participation in the body’s immune responses, and prevention of infections. C/EBPε function is regulated by phosphorylation, acetylation, methylation, and other types of genes. This review related to C/EBPε structure, function and regulation provides a theoretical basis for subsequent research in this area. C/EBPε is an emerging therapeutic target and thus provides new strategies for disease prevention and control.https://doi.org/10.1177/1721727X231153322
spellingShingle Shaowen Cheng
Jian Yang
Yudie Wang
Lina Xian
Zhihua Hu
Lingyun Zou
The function and regulation of CCAAT/enhancer binding protein ε
European Journal of Inflammation
title The function and regulation of CCAAT/enhancer binding protein ε
title_full The function and regulation of CCAAT/enhancer binding protein ε
title_fullStr The function and regulation of CCAAT/enhancer binding protein ε
title_full_unstemmed The function and regulation of CCAAT/enhancer binding protein ε
title_short The function and regulation of CCAAT/enhancer binding protein ε
title_sort function and regulation of ccaat enhancer binding protein ε
url https://doi.org/10.1177/1721727X231153322
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