Modified Cangfu Daotan decoction ameliorates polycystic ovary syndrome with insulin resistance via NF-κB/LCN-2 signaling pathway in inflammatory microenvironment

Modified Cangfu Daotan decoction ameliorates polycystic ovary syndrome with insulin resistance via NF-κB/LCN-2 signaling pathway in inflammatory microenvironment

This study explored the possible connection between the insulin resistance-targeting protein adipokine lipocalin-2 (LCN-2) and NF-κB signaling pathway in the inflammatory microenvironment in PCOS-IR model rats to determine the pharmacological mechanism of modified Cangfu Daotan decoction (MCDD) inte...

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Bibliographic Details
Main Authors: Shuowen Liu, Yao Zhang, Fang Yang, Jingna Gu, Ruyue Zhang, Yingying Kuang, Wantong Mai, Chengbo Zheng, Yang Yu, Ruling Lu, Lei Zeng, Hongying Cao, Yongling Long
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Endocrinology
Subjects:
Lcn-2
NF-kB signaling pathway
INSR/IRS-1/GLUT4
PCOS-IR
Modified Cangfu Daotan decoction
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2022.975724/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2022.975724/full

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