Nocardia Asteroides Keratitis: Report of seven patients and literature review

<b>Purpose:</b> To describe clinical features and treatment outcomes in patients with advanced <i>Nocardia asteroides</i> keratitis. <b>Methods:</b> Retrospective review of case records of 7 patients with culture-proven <i>Nocardia</i> keratitis. <b...

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Main Authors: Rao Srinivas, Madhavan Hajib, Sitalakshmi G, Padmanabhan Prema
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2000-01-01
Series:Indian Journal of Ophthalmology
Subjects:
Online Access:http://www.ijo.in/article.asp?issn=0301-4738;year=2000;volume=48;issue=3;spage=217;epage=21;aulast=Rao
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author Rao Srinivas
Madhavan Hajib
Sitalakshmi G
Padmanabhan Prema
author_facet Rao Srinivas
Madhavan Hajib
Sitalakshmi G
Padmanabhan Prema
author_sort Rao Srinivas
collection DOAJ
description <b>Purpose:</b> To describe clinical features and treatment outcomes in patients with advanced <i>Nocardia asteroides</i> keratitis. <b>Methods:</b> Retrospective review of case records of 7 patients with culture-proven <i>Nocardia</i> keratitis. <b>Results:</b> Corneal infection occurred after corneal trauma in two patients, cataract surgery in three patients, penetrating keratoplasty in one patient and was associated with a silicone buckle element infection in one patient. Mean duration of infection at presentation was 33.4 days (7-75 days), and five patients had received prior treatment with corticosteroids. Six of seven patients had deep corneal suppuration at the time of: presentation, clinically suggestive of mycotic keratitis. In two patients who had received prolonged corticosteroid therapy (&#x0026;#8805; 45 days), the eyes could not be salvaged. Complete resolution of infection was achieved in all 4 eyes treated with topical fortified cefazolin eye drops (50mg / ml).
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spelling doaj.art-12caf3761191416aa41f20e5ec88808e2022-12-22T03:18:40ZengWolters Kluwer Medknow PublicationsIndian Journal of Ophthalmology0301-47382000-01-0148321721Nocardia Asteroides Keratitis: Report of seven patients and literature reviewRao SrinivasMadhavan HajibSitalakshmi GPadmanabhan Prema<b>Purpose:</b> To describe clinical features and treatment outcomes in patients with advanced <i>Nocardia asteroides</i> keratitis. <b>Methods:</b> Retrospective review of case records of 7 patients with culture-proven <i>Nocardia</i> keratitis. <b>Results:</b> Corneal infection occurred after corneal trauma in two patients, cataract surgery in three patients, penetrating keratoplasty in one patient and was associated with a silicone buckle element infection in one patient. Mean duration of infection at presentation was 33.4 days (7-75 days), and five patients had received prior treatment with corticosteroids. Six of seven patients had deep corneal suppuration at the time of: presentation, clinically suggestive of mycotic keratitis. In two patients who had received prolonged corticosteroid therapy (&#x0026;#8805; 45 days), the eyes could not be salvaged. Complete resolution of infection was achieved in all 4 eyes treated with topical fortified cefazolin eye drops (50mg / ml).http://www.ijo.in/article.asp?issn=0301-4738;year=2000;volume=48;issue=3;spage=217;epage=21;aulast=RaoAdolescentAdultAgedCefazolinadministration &#x0026;amp; dosageCephalosporinsadministration &#x0026;amp; dosageChildChildPreschoolComparative Study
spellingShingle Rao Srinivas
Madhavan Hajib
Sitalakshmi G
Padmanabhan Prema
Nocardia Asteroides Keratitis: Report of seven patients and literature review
Indian Journal of Ophthalmology
Adolescent
Adult
Aged
Cefazolin
administration &#x0026;amp; dosage
Cephalosporins
administration &#x0026;amp; dosage
Child
Child
Preschool
Comparative Study
title Nocardia Asteroides Keratitis: Report of seven patients and literature review
title_full Nocardia Asteroides Keratitis: Report of seven patients and literature review
title_fullStr Nocardia Asteroides Keratitis: Report of seven patients and literature review
title_full_unstemmed Nocardia Asteroides Keratitis: Report of seven patients and literature review
title_short Nocardia Asteroides Keratitis: Report of seven patients and literature review
title_sort nocardia asteroides keratitis report of seven patients and literature review
topic Adolescent
Adult
Aged
Cefazolin
administration &#x0026;amp; dosage
Cephalosporins
administration &#x0026;amp; dosage
Child
Child
Preschool
Comparative Study
url http://www.ijo.in/article.asp?issn=0301-4738;year=2000;volume=48;issue=3;spage=217;epage=21;aulast=Rao
work_keys_str_mv AT raosrinivas nocardiaasteroideskeratitisreportofsevenpatientsandliteraturereview
AT madhavanhajib nocardiaasteroideskeratitisreportofsevenpatientsandliteraturereview
AT sitalakshmig nocardiaasteroideskeratitisreportofsevenpatientsandliteraturereview
AT padmanabhanprema nocardiaasteroideskeratitisreportofsevenpatientsandliteraturereview