Importance of diagnostic laboratory methods of beta hemolytic streptococcus group A in comparison with clinical findings in the diagnosis of streptococcal sore throat and unnecessary antibacterial therapy
Background: Streptococcus Pyogenes (group A streptococcus, GAS) is the most important cause of bacterial pharyngitis in children and adolescents. Acute pharyngitis is one of the most common conditions in all ages but it is most common in children. Over diagnosis of acute pharyngitis represents one o...
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| Format: | Article |
| Language: | English |
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Bushehr University of Medical Sciences
2012-04-01
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| Series: | Iranian South Medical Journal |
| Subjects: | |
| Online Access: | http://ismj.bpums.ac.ir/browse.php?a_code=A-10-3-253&slc_lang=en&sid=1 |
| _version_ | 1811247736316493824 |
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| author | Peiman Eini Ahmadreza Mobaien Mehdi Agha Sharif |
| author_facet | Peiman Eini Ahmadreza Mobaien Mehdi Agha Sharif |
| author_sort | Peiman Eini |
| collection | DOAJ |
| description | Background: Streptococcus Pyogenes (group A streptococcus, GAS) is the most important cause of bacterial pharyngitis in children and adolescents. Acute pharyngitis is one of the most common conditions in all ages but it is most common in children. Over diagnosis of acute pharyngitis represents one of the major causes of antibiotic abuse. The goal of this study is to make an estimate of the frequency of group A streptococcus in sore throat patients in Farshchian hospital emergency department and clinic in Hamadan. Methods: For estimation of the clinical features role in diagnosis of streptococcal sore throat, we took samples of 100 patients with average age of 32.96±29.86 years with sore throat. We took samples from pharynx and used standard methods of bacteriology in order to detect streptococcus. Results: Group A Streptococcus (GAS) accounts for 3 percent of all cases of pharyngitis. Clinically, all of the patients had sore throat. The percent breakdowns are as follows: 30% had exudate, 78% had fever, 8% had lymphadenopathy and 7.7 percent of exudative pharyngitis was streptococcal. The cost for unnecessary antibiotic therapy for every single patient who had negative pharynx culture was approximately 32160 Rails. Conclusion: The low frequency of streptococcus pharyngitis in treated patients reveal that diagnosis based on clinical features is not reliable. We recommend use of other diagnostic methods such as Rapid Antigen Detection Tests (RATs). Only reliable and scientific protocols for antibiotic to therapy. |
| first_indexed | 2024-04-12T15:14:53Z |
| format | Article |
| id | doaj.art-12cd8170cd1949679f7e5709f92691f2 |
| institution | Directory Open Access Journal |
| issn | 1735-4374 1735-6954 |
| language | English |
| last_indexed | 2024-04-12T15:14:53Z |
| publishDate | 2012-04-01 |
| publisher | Bushehr University of Medical Sciences |
| record_format | Article |
| series | Iranian South Medical Journal |
| spelling | doaj.art-12cd8170cd1949679f7e5709f92691f22022-12-22T03:27:38ZengBushehr University of Medical SciencesIranian South Medical Journal1735-43741735-69542012-04-011515968Importance of diagnostic laboratory methods of beta hemolytic streptococcus group A in comparison with clinical findings in the diagnosis of streptococcal sore throat and unnecessary antibacterial therapyPeiman Eini0Ahmadreza Mobaien1Mehdi Agha Sharif2 Hamadan University of Medical Sciences, Hamadan, IRAN Zanjan University of Medical Sciences, Sistan Baloochestan, IRAN School of Medicine, Hamadan University of Medical Sciences, Hamadan, IRAN Background: Streptococcus Pyogenes (group A streptococcus, GAS) is the most important cause of bacterial pharyngitis in children and adolescents. Acute pharyngitis is one of the most common conditions in all ages but it is most common in children. Over diagnosis of acute pharyngitis represents one of the major causes of antibiotic abuse. The goal of this study is to make an estimate of the frequency of group A streptococcus in sore throat patients in Farshchian hospital emergency department and clinic in Hamadan. Methods: For estimation of the clinical features role in diagnosis of streptococcal sore throat, we took samples of 100 patients with average age of 32.96±29.86 years with sore throat. We took samples from pharynx and used standard methods of bacteriology in order to detect streptococcus. Results: Group A Streptococcus (GAS) accounts for 3 percent of all cases of pharyngitis. Clinically, all of the patients had sore throat. The percent breakdowns are as follows: 30% had exudate, 78% had fever, 8% had lymphadenopathy and 7.7 percent of exudative pharyngitis was streptococcal. The cost for unnecessary antibiotic therapy for every single patient who had negative pharynx culture was approximately 32160 Rails. Conclusion: The low frequency of streptococcus pharyngitis in treated patients reveal that diagnosis based on clinical features is not reliable. We recommend use of other diagnostic methods such as Rapid Antigen Detection Tests (RATs). Only reliable and scientific protocols for antibiotic to therapy.http://ismj.bpums.ac.ir/browse.php?a_code=A-10-3-253&slc_lang=en&sid=1sore Throat group A beta-hemolytic streptococci antibacterial therapy cervical adenopathy |
| spellingShingle | Peiman Eini Ahmadreza Mobaien Mehdi Agha Sharif Importance of diagnostic laboratory methods of beta hemolytic streptococcus group A in comparison with clinical findings in the diagnosis of streptococcal sore throat and unnecessary antibacterial therapy Iranian South Medical Journal sore Throat group A beta-hemolytic streptococci antibacterial therapy cervical adenopathy |
| title | Importance of diagnostic laboratory methods of beta hemolytic streptococcus group A in comparison with clinical findings in the diagnosis of streptococcal sore throat and unnecessary antibacterial therapy |
| title_full | Importance of diagnostic laboratory methods of beta hemolytic streptococcus group A in comparison with clinical findings in the diagnosis of streptococcal sore throat and unnecessary antibacterial therapy |
| title_fullStr | Importance of diagnostic laboratory methods of beta hemolytic streptococcus group A in comparison with clinical findings in the diagnosis of streptococcal sore throat and unnecessary antibacterial therapy |
| title_full_unstemmed | Importance of diagnostic laboratory methods of beta hemolytic streptococcus group A in comparison with clinical findings in the diagnosis of streptococcal sore throat and unnecessary antibacterial therapy |
| title_short | Importance of diagnostic laboratory methods of beta hemolytic streptococcus group A in comparison with clinical findings in the diagnosis of streptococcal sore throat and unnecessary antibacterial therapy |
| title_sort | importance of diagnostic laboratory methods of beta hemolytic streptococcus group a in comparison with clinical findings in the diagnosis of streptococcal sore throat and unnecessary antibacterial therapy |
| topic | sore Throat group A beta-hemolytic streptococci antibacterial therapy cervical adenopathy |
| url | http://ismj.bpums.ac.ir/browse.php?a_code=A-10-3-253&slc_lang=en&sid=1 |
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