| Summary: | This retrospective cohort study aimed to analyze the clinical manifestations, complications, and maternal-fetal outcomes in patients affected by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection during delivery. The cohort included 61 pregnant women positive for SARS-CoV-2 infection at the time of delivery. Patients were divided into two groups: symptomatic and asymptomatic. We found a significantly higher rate of leukocytosis (<i>p</i> < 0.00078) and lymphopenia (<i>p</i> < 0.0024) in symptomatic women compared with asymptomatic ones. Other laboratory parameters, such as CRP (<i>p</i> = 0.002), AST (<i>p</i> = 0.007), LDH (<i>p</i> = 0.0142), ferritin (<i>p</i> = 0.0036), and D-dimer (<i>p</i> = 0.00124), were also significantly more often increased in the group of symptomatic pregnant women. Overall, symptomatic pregnant women with SARS-CoV-2 infection at the delivery show more often altered laboratory parameters compared with asymptomatic ones; nevertheless, they have a slightly higher but non-significant rate of preterm delivery, cesarean section, as well as lower neonatal birth weight and Apgar score, compared with asymptomatic women.
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