Hemodynamics and Gas Exchange Effects of Inhaled Nitrous Oxide in Patients with Acute Respiratory Distress Syndrome

Inhaled nitrous oxide (iNO) therapy aimed at improving pulmonary oxygenizing function and at decreasing artificial ventilation (AV) load has been used in foreign clinical practice in the past decade. The study was undertaken to evaluate the hemodynamic and gas exchange effects of iNO in acute respir...

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Main Author: V. N. Poptsov
Format: Article
Language:English
Published: Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia 2006-04-01
Series:Общая реаниматология
Subjects:
Online Access:https://www.reanimatology.com/rmt/article/view/1167
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author V. N. Poptsov
author_facet V. N. Poptsov
author_sort V. N. Poptsov
collection DOAJ
description Inhaled nitrous oxide (iNO) therapy aimed at improving pulmonary oxygenizing function and at decreasing artificial ventilation (AV) load has been used in foreign clinical practice in the past decade. The study was undertaken to evaluate the hemodynamic and gas exchange effects of iNO in acute respiratory distress syndrome (ARDS) that developed after car-diosurgical operations. Fifty-eight (43 males and 15 females) patients aged 21 to 76 (55.2±2.4) years were examined. The study has demonstrated that in 48.3% of cases, the early stage of ARDS is attended by the increased tone pulmonary vessels due to impaired NO-dependent vasodilatation. In these patients, iNO therapy is an effective therapeutic method for correcting hemodynamic disorders and lung oxygenizing function.
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spelling doaj.art-12d1c40c43824878a18f6b4be283c9f02023-03-13T09:32:46ZengFederal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, RussiaОбщая реаниматология1813-97792411-71102006-04-0122141910.15360/1813-9779-2006-2-14-191167Hemodynamics and Gas Exchange Effects of Inhaled Nitrous Oxide in Patients with Acute Respiratory Distress SyndromeV. N. Poptsov0ФГУ НИИ Трансплантологии и искусственных органов РОСЗДРАВАInhaled nitrous oxide (iNO) therapy aimed at improving pulmonary oxygenizing function and at decreasing artificial ventilation (AV) load has been used in foreign clinical practice in the past decade. The study was undertaken to evaluate the hemodynamic and gas exchange effects of iNO in acute respiratory distress syndrome (ARDS) that developed after car-diosurgical operations. Fifty-eight (43 males and 15 females) patients aged 21 to 76 (55.2±2.4) years were examined. The study has demonstrated that in 48.3% of cases, the early stage of ARDS is attended by the increased tone pulmonary vessels due to impaired NO-dependent vasodilatation. In these patients, iNO therapy is an effective therapeutic method for correcting hemodynamic disorders and lung oxygenizing function.https://www.reanimatology.com/rmt/article/view/1167острый респираторный дистресс-синдромингаляционный оксид азота
spellingShingle V. N. Poptsov
Hemodynamics and Gas Exchange Effects of Inhaled Nitrous Oxide in Patients with Acute Respiratory Distress Syndrome
Общая реаниматология
острый респираторный дистресс-синдром
ингаляционный оксид азота
title Hemodynamics and Gas Exchange Effects of Inhaled Nitrous Oxide in Patients with Acute Respiratory Distress Syndrome
title_full Hemodynamics and Gas Exchange Effects of Inhaled Nitrous Oxide in Patients with Acute Respiratory Distress Syndrome
title_fullStr Hemodynamics and Gas Exchange Effects of Inhaled Nitrous Oxide in Patients with Acute Respiratory Distress Syndrome
title_full_unstemmed Hemodynamics and Gas Exchange Effects of Inhaled Nitrous Oxide in Patients with Acute Respiratory Distress Syndrome
title_short Hemodynamics and Gas Exchange Effects of Inhaled Nitrous Oxide in Patients with Acute Respiratory Distress Syndrome
title_sort hemodynamics and gas exchange effects of inhaled nitrous oxide in patients with acute respiratory distress syndrome
topic острый респираторный дистресс-синдром
ингаляционный оксид азота
url https://www.reanimatology.com/rmt/article/view/1167
work_keys_str_mv AT vnpoptsov hemodynamicsandgasexchangeeffectsofinhalednitrousoxideinpatientswithacuterespiratorydistresssyndrome