Original paper<br>Estimation of cardiovascular complications and death risk in subjects with metabolic syndrome

Introduction: Coexistence of lipid and carbohydrate disorders with hypertension and obesity increases the risk of ischaemic heart disease and its complications. The recently observed lack of reduction in the incidence of cardiovascular system diseases is thought to be due to the growing epidemic of...

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Main Authors: Jan Kowalski, Marcin Barylski, Małgorzata Godala, Robert Irzmański, Ewa Brocka, Lucjan Pawlicki
Format: Article
Language:English
Published: Termedia Publishing House 2006-12-01
Series:Archives of Medical Science
Subjects:
Online Access:http://www.termedia.pl/magazine.php?magazine_id=19&article_id=7337&magazine_subpage=FULL_TEXT
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author Jan Kowalski
Marcin Barylski
Małgorzata Godala
Robert Irzmański
Ewa Brocka
Lucjan Pawlicki
author_facet Jan Kowalski
Marcin Barylski
Małgorzata Godala
Robert Irzmański
Ewa Brocka
Lucjan Pawlicki
author_sort Jan Kowalski
collection DOAJ
description Introduction: Coexistence of lipid and carbohydrate disorders with hypertension and obesity increases the risk of ischaemic heart disease and its complications. The recently observed lack of reduction in the incidence of cardiovascular system diseases is thought to be due to the growing epidemic of MS. The aim of the study was to estimate cardiovascular complications and death risk in subjects with MS. Material and methods: The prevention study included 581 subjects (213 males and 368 females): 250 born in 1949, 155 born in 1959 and 176 born in 1969. MS was diagnosed (on the basis of NCEP ATP III) in 104 individuals. Increased risk of cardiovascular complications was determined for pulse pressure (pp) >63 mmHg. Based on the SCORE index (algorithm), 10-year death risk due to cardiovascular complications was estimated taking into account sex, age, smoking, systolic blood pressure and total cholesterol concentration. A value ³5% was accepted as high risk of death within 10 years. Results: Increased risk of cardiovascular complications (pp >63 mmHg) was found in 21 subjects (20.2%) with MS and 34 (7.1%) without MS (p<0.05). High death risk due to cardiovascular complications (within 10 years, ³5%) was diagnosed in 33 (31.7%) subjects with MS and in 38 (8%) without MS (p<0.05). Conclusions: High risk of cardiovascular complications and death occurs statistically more frequently in subjects with MS than in the rest of the population.
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spelling doaj.art-12d26cd4735a4a2fbb326d68aef077d22022-12-21T17:16:46ZengTermedia Publishing HouseArchives of Medical Science1734-19222006-12-0124252255Original paper<br>Estimation of cardiovascular complications and death risk in subjects with metabolic syndromeJan KowalskiMarcin BarylskiMałgorzata GodalaRobert IrzmańskiEwa BrockaLucjan PawlickiIntroduction: Coexistence of lipid and carbohydrate disorders with hypertension and obesity increases the risk of ischaemic heart disease and its complications. The recently observed lack of reduction in the incidence of cardiovascular system diseases is thought to be due to the growing epidemic of MS. The aim of the study was to estimate cardiovascular complications and death risk in subjects with MS. Material and methods: The prevention study included 581 subjects (213 males and 368 females): 250 born in 1949, 155 born in 1959 and 176 born in 1969. MS was diagnosed (on the basis of NCEP ATP III) in 104 individuals. Increased risk of cardiovascular complications was determined for pulse pressure (pp) >63 mmHg. Based on the SCORE index (algorithm), 10-year death risk due to cardiovascular complications was estimated taking into account sex, age, smoking, systolic blood pressure and total cholesterol concentration. A value ³5% was accepted as high risk of death within 10 years. Results: Increased risk of cardiovascular complications (pp >63 mmHg) was found in 21 subjects (20.2%) with MS and 34 (7.1%) without MS (p<0.05). High death risk due to cardiovascular complications (within 10 years, ³5%) was diagnosed in 33 (31.7%) subjects with MS and in 38 (8%) without MS (p<0.05). Conclusions: High risk of cardiovascular complications and death occurs statistically more frequently in subjects with MS than in the rest of the population.http://www.termedia.pl/magazine.php?magazine_id=19&article_id=7337&magazine_subpage=FULL_TEXTmetabolic syndromecardiovascular complicationsdeath riskpulse pressureSCORE index
spellingShingle Jan Kowalski
Marcin Barylski
Małgorzata Godala
Robert Irzmański
Ewa Brocka
Lucjan Pawlicki
Original paper<br>Estimation of cardiovascular complications and death risk in subjects with metabolic syndrome
Archives of Medical Science
metabolic syndrome
cardiovascular complications
death risk
pulse pressure
SCORE index
title Original paper<br>Estimation of cardiovascular complications and death risk in subjects with metabolic syndrome
title_full Original paper<br>Estimation of cardiovascular complications and death risk in subjects with metabolic syndrome
title_fullStr Original paper<br>Estimation of cardiovascular complications and death risk in subjects with metabolic syndrome
title_full_unstemmed Original paper<br>Estimation of cardiovascular complications and death risk in subjects with metabolic syndrome
title_short Original paper<br>Estimation of cardiovascular complications and death risk in subjects with metabolic syndrome
title_sort original paper br estimation of cardiovascular complications and death risk in subjects with metabolic syndrome
topic metabolic syndrome
cardiovascular complications
death risk
pulse pressure
SCORE index
url http://www.termedia.pl/magazine.php?magazine_id=19&article_id=7337&magazine_subpage=FULL_TEXT
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