Invasome: A Novel Nanocarrier for Transdermal Drug Delivery
Invasomes are novel vesicular systems that exhibit improved transdermal penetration compared to conventional liposomes. These vesicles contain phospholipids, ethanol, and terpene in their structures; these components confer suitable transdermal penetration properties to the soft vesicles. The main a...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-02-01
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| Series: | Nanomaterials |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2079-4991/10/2/341 |
| _version_ | 1818050090910089216 |
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| author | Soraya Babaie Azizeh Rahmani Del Bakhshayesh Ji Won Ha Hamed Hamishehkar Ki Hyun Kim |
| author_facet | Soraya Babaie Azizeh Rahmani Del Bakhshayesh Ji Won Ha Hamed Hamishehkar Ki Hyun Kim |
| author_sort | Soraya Babaie |
| collection | DOAJ |
| description | Invasomes are novel vesicular systems that exhibit improved transdermal penetration compared to conventional liposomes. These vesicles contain phospholipids, ethanol, and terpene in their structures; these components confer suitable transdermal penetration properties to the soft vesicles. The main advantages of these nanovesicles lie in their ability to increase the permeability of the drug into the skin and decrease absorption into the systemic circulation, thus, limiting the activity of various drugs within the skin layer. In this paper, several features of invasomes, including their structure, mechanism of penetration, applications, characterization, and potential advantages in dermal drug delivery, are highlighted. Overall, this review suggests that enhanced transdermal penetration of drugs using invasomes provides an appropriate opportunity for the development of lipid vesicular carriers. |
| first_indexed | 2024-12-10T10:47:57Z |
| format | Article |
| id | doaj.art-12d5193609614121a7c9fc157b6fb6a0 |
| institution | Directory Open Access Journal |
| issn | 2079-4991 |
| language | English |
| last_indexed | 2024-12-10T10:47:57Z |
| publishDate | 2020-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nanomaterials |
| spelling | doaj.art-12d5193609614121a7c9fc157b6fb6a02022-12-22T01:52:06ZengMDPI AGNanomaterials2079-49912020-02-0110234110.3390/nano10020341nano10020341Invasome: A Novel Nanocarrier for Transdermal Drug DeliverySoraya Babaie0Azizeh Rahmani Del Bakhshayesh1Ji Won Ha2Hamed Hamishehkar3Ki Hyun Kim4Biotechnology Research Center, Student Research Committee, and Faculty of Advanced Medical Science, Tabriz University of Medical Sciences, Tabriz 51368, IranStem Cell and Regenerative Medicine Institute, and Department of Tissue Engineering, Faculty of Advanced Medical Sciences, Tabriz University of Medical Sciences, Tabriz 51368, IranSchool of Pharmacy, Sungkyunkwan University, Suwon 16419, KoreaDrug Applied Research Center, Tabriz University of Medical Sciences, Tabriz 51368, IranSchool of Pharmacy, Sungkyunkwan University, Suwon 16419, KoreaInvasomes are novel vesicular systems that exhibit improved transdermal penetration compared to conventional liposomes. These vesicles contain phospholipids, ethanol, and terpene in their structures; these components confer suitable transdermal penetration properties to the soft vesicles. The main advantages of these nanovesicles lie in their ability to increase the permeability of the drug into the skin and decrease absorption into the systemic circulation, thus, limiting the activity of various drugs within the skin layer. In this paper, several features of invasomes, including their structure, mechanism of penetration, applications, characterization, and potential advantages in dermal drug delivery, are highlighted. Overall, this review suggests that enhanced transdermal penetration of drugs using invasomes provides an appropriate opportunity for the development of lipid vesicular carriers.https://www.mdpi.com/2079-4991/10/2/341transdermalliposomeinvasometerpenenanocarrier |
| spellingShingle | Soraya Babaie Azizeh Rahmani Del Bakhshayesh Ji Won Ha Hamed Hamishehkar Ki Hyun Kim Invasome: A Novel Nanocarrier for Transdermal Drug Delivery Nanomaterials transdermal liposome invasome terpene nanocarrier |
| title | Invasome: A Novel Nanocarrier for Transdermal Drug Delivery |
| title_full | Invasome: A Novel Nanocarrier for Transdermal Drug Delivery |
| title_fullStr | Invasome: A Novel Nanocarrier for Transdermal Drug Delivery |
| title_full_unstemmed | Invasome: A Novel Nanocarrier for Transdermal Drug Delivery |
| title_short | Invasome: A Novel Nanocarrier for Transdermal Drug Delivery |
| title_sort | invasome a novel nanocarrier for transdermal drug delivery |
| topic | transdermal liposome invasome terpene nanocarrier |
| url | https://www.mdpi.com/2079-4991/10/2/341 |
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