Prevalence of Infection and Appropriate Antibiotic Treatment in Brain-Dead Organ Donors

Purpose: Infection control of the brain-dead donors (BDDs) is crucial to improve graft quality and ensure safety of the recipients. Sparse clinical data about infection of BDD in Korea poses difficulties in choice of antibiotics. We conducted this study to estimate the prevalence of infection and su...

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Main Authors: Yo Hwan Kim, Hong Rae Cho, Byung Kyun Ko, Yang Won Nah, Chang Woo Nam, Sang Jun Park, Song-Soo Yang, Kyu-Hyouck Kyoung
Format: Article
Language:English
Published: Korean Society of Acute Care Surgery 2015-04-01
Series:Journal of Acute Care Surgery
Subjects:
Online Access:http://www.jacs.or.kr/upload/pdf/jacs-5-15.pdf
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author Yo Hwan Kim
Hong Rae Cho
Byung Kyun Ko
Yang Won Nah
Chang Woo Nam
Sang Jun Park
Song-Soo Yang
Kyu-Hyouck Kyoung
author_facet Yo Hwan Kim
Hong Rae Cho
Byung Kyun Ko
Yang Won Nah
Chang Woo Nam
Sang Jun Park
Song-Soo Yang
Kyu-Hyouck Kyoung
author_sort Yo Hwan Kim
collection DOAJ
description Purpose: Infection control of the brain-dead donors (BDDs) is crucial to improve graft quality and ensure safety of the recipients. Sparse clinical data about infection of BDD in Korea poses difficulties in choice of antibiotics. We conducted this study to estimate the prevalence of infection and suitability of antibiotic treatment in BDDs. Methods: A retrospective analysis of BDDs between January 2009 and December 2013 was conducted. Types of microbes and prevalence of multi-drug resistant organisms (MDRO) by hospital stay were analyzed. Results: The most common site of infection was the respiratory tract, and seven (12.7%) patients had bacteremia. The overall prevalence of MDRO was 34.5%, although in BDDs with hospital stay more than 16 days that increased to 66.7%. Antibiotic treatment was used at least in days 6~10 of the hospital stay. Conclusion: Infection control of BDDs is essential for transplantation. The development of MDRO and suitability of antibiotics need evaluation.
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spelling doaj.art-12d7a6bef5a046a9b765ddd2876811f52023-09-18T06:08:21ZengKorean Society of Acute Care SurgeryJournal of Acute Care Surgery2288-58622288-95822015-04-0151151810.17479/jacs.2015.5.1.155Prevalence of Infection and Appropriate Antibiotic Treatment in Brain-Dead Organ DonorsYo Hwan Kim0Hong Rae Cho1Byung Kyun Ko2Yang Won Nah3Chang Woo Nam4Sang Jun Park5Song-Soo Yang6Kyu-Hyouck Kyoung7 Department of Surgery, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Korea Department of Surgery, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Korea Department of Surgery, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Korea Department of Surgery, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Korea Department of Surgery, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Korea Department of Surgery, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Korea Department of Surgery, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Korea Department of Surgery, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Korea Purpose: Infection control of the brain-dead donors (BDDs) is crucial to improve graft quality and ensure safety of the recipients. Sparse clinical data about infection of BDD in Korea poses difficulties in choice of antibiotics. We conducted this study to estimate the prevalence of infection and suitability of antibiotic treatment in BDDs. Methods: A retrospective analysis of BDDs between January 2009 and December 2013 was conducted. Types of microbes and prevalence of multi-drug resistant organisms (MDRO) by hospital stay were analyzed. Results: The most common site of infection was the respiratory tract, and seven (12.7%) patients had bacteremia. The overall prevalence of MDRO was 34.5%, although in BDDs with hospital stay more than 16 days that increased to 66.7%. Antibiotic treatment was used at least in days 6~10 of the hospital stay. Conclusion: Infection control of BDDs is essential for transplantation. The development of MDRO and suitability of antibiotics need evaluation.http://www.jacs.or.kr/upload/pdf/jacs-5-15.pdfbrain-dead donorinfectionmulti-drug resistant organism
spellingShingle Yo Hwan Kim
Hong Rae Cho
Byung Kyun Ko
Yang Won Nah
Chang Woo Nam
Sang Jun Park
Song-Soo Yang
Kyu-Hyouck Kyoung
Prevalence of Infection and Appropriate Antibiotic Treatment in Brain-Dead Organ Donors
Journal of Acute Care Surgery
brain-dead donor
infection
multi-drug resistant organism
title Prevalence of Infection and Appropriate Antibiotic Treatment in Brain-Dead Organ Donors
title_full Prevalence of Infection and Appropriate Antibiotic Treatment in Brain-Dead Organ Donors
title_fullStr Prevalence of Infection and Appropriate Antibiotic Treatment in Brain-Dead Organ Donors
title_full_unstemmed Prevalence of Infection and Appropriate Antibiotic Treatment in Brain-Dead Organ Donors
title_short Prevalence of Infection and Appropriate Antibiotic Treatment in Brain-Dead Organ Donors
title_sort prevalence of infection and appropriate antibiotic treatment in brain dead organ donors
topic brain-dead donor
infection
multi-drug resistant organism
url http://www.jacs.or.kr/upload/pdf/jacs-5-15.pdf
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