Mice lacking the p43 mitochondrial T3 receptor become glucose intolerant and insulin resistant during aging.

Mice lacking the p43 mitochondrial T3 receptor become glucose intolerant and insulin resistant during aging.

Thyroid hormones (TH) play an important regulatory role in energy expenditure regulation and are key regulators of mitochondrial activity. We have previously identified a mitochondrial triiodothyronine (T3) receptor (p43) which acts as a mitochondrial transcription factor of the organelle genome, wh...

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Bibliographic Details
Main Authors: Christelle Bertrand, Emilie Blanchet, Laurence Pessemesse, Jean Sébastien Annicotte, Christine Feillet-Coudray, Béatrice Chabi, Jonathan Levin, Lluis Fajas, Gérard Cabello, Chantal Wrutniak-Cabello, François Casas
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3787095?pdf=render

Internet

http://europepmc.org/articles/PMC3787095?pdf=render

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