Concomitant atopic dermatitis and psoriasis – a retrospective review
Introduction At one time considered opposing diseases, it is now recognized that atopic dermatitis (AD) and psoriasis can coexist. There are limited data characterizing this population of patients. In this study, we characterize the population of patients diagnosed with both AD and psoriasis and sum...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2021-10-01
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| Series: | Journal of Dermatological Treatment |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1080/09546634.2019.1702147 |
| _version_ | 1797683586888892416 |
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| author | Kelly Barry Pedro Zancanaro Rachel Casseres Rana Abdat Nicole Dumont David Rosmarin |
| author_facet | Kelly Barry Pedro Zancanaro Rachel Casseres Rana Abdat Nicole Dumont David Rosmarin |
| author_sort | Kelly Barry |
| collection | DOAJ |
| description | Introduction At one time considered opposing diseases, it is now recognized that atopic dermatitis (AD) and psoriasis can coexist. There are limited data characterizing this population of patients. In this study, we characterize the population of patients diagnosed with both AD and psoriasis and summarize their response to therapy. Methods A retrospective chart review was performed and data was recorded for patients with a diagnosis of psoriasis (n = 1390), AD (n = 912) and psoriasis plus AD (n = 30) within the Tufts Medical Center Department of Dermatology between January 1, 2012 and May 1, 2019. Results The prevalence of concomitant AD and psoriasis was 1.5%. Of those with both AD and psoriasis, hand involvement was high (63%). Systemic therapy was used in 73% of patients. Of those on biologics, 30% required more than one biologic consecutively and 22% required more than one biologic simultaneously to achieve clinically significant results. Conclusion Patients with overlapping AD and psoriasis have a high prevalence of hand involvement, poor response to topical therapy, and may require multiple systemic agents to treat. In a patient with known history of psoriasis with recalcitrant hand disease involvement, AD should be considered. |
| first_indexed | 2024-03-12T00:17:41Z |
| format | Article |
| id | doaj.art-12dbb0446c4a41ec87213dc0e4963171 |
| institution | Directory Open Access Journal |
| issn | 0954-6634 1471-1753 |
| language | English |
| last_indexed | 2024-03-12T00:17:41Z |
| publishDate | 2021-10-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Journal of Dermatological Treatment |
| spelling | doaj.art-12dbb0446c4a41ec87213dc0e49631712023-09-15T14:23:04ZengTaylor & Francis GroupJournal of Dermatological Treatment0954-66341471-17532021-10-0132771672010.1080/09546634.2019.17021471702147Concomitant atopic dermatitis and psoriasis – a retrospective reviewKelly Barry0Pedro Zancanaro1Rachel Casseres2Rana Abdat3Nicole Dumont4David Rosmarin5Tufts University School of MedicineDepartment of Dermatology, Tufts Medical CenterTufts University School of MedicineDepartment of Dermatology, Tufts Medical CenterDepartment of Dermatology, Tufts Medical CenterDepartment of Dermatology, Tufts Medical CenterIntroduction At one time considered opposing diseases, it is now recognized that atopic dermatitis (AD) and psoriasis can coexist. There are limited data characterizing this population of patients. In this study, we characterize the population of patients diagnosed with both AD and psoriasis and summarize their response to therapy. Methods A retrospective chart review was performed and data was recorded for patients with a diagnosis of psoriasis (n = 1390), AD (n = 912) and psoriasis plus AD (n = 30) within the Tufts Medical Center Department of Dermatology between January 1, 2012 and May 1, 2019. Results The prevalence of concomitant AD and psoriasis was 1.5%. Of those with both AD and psoriasis, hand involvement was high (63%). Systemic therapy was used in 73% of patients. Of those on biologics, 30% required more than one biologic consecutively and 22% required more than one biologic simultaneously to achieve clinically significant results. Conclusion Patients with overlapping AD and psoriasis have a high prevalence of hand involvement, poor response to topical therapy, and may require multiple systemic agents to treat. In a patient with known history of psoriasis with recalcitrant hand disease involvement, AD should be considered.http://dx.doi.org/10.1080/09546634.2019.1702147palmoplantar psoriasishand eczemaatopic dermatitisbiologic |
| spellingShingle | Kelly Barry Pedro Zancanaro Rachel Casseres Rana Abdat Nicole Dumont David Rosmarin Concomitant atopic dermatitis and psoriasis – a retrospective review Journal of Dermatological Treatment palmoplantar psoriasis hand eczema atopic dermatitis biologic |
| title | Concomitant atopic dermatitis and psoriasis – a retrospective review |
| title_full | Concomitant atopic dermatitis and psoriasis – a retrospective review |
| title_fullStr | Concomitant atopic dermatitis and psoriasis – a retrospective review |
| title_full_unstemmed | Concomitant atopic dermatitis and psoriasis – a retrospective review |
| title_short | Concomitant atopic dermatitis and psoriasis – a retrospective review |
| title_sort | concomitant atopic dermatitis and psoriasis a retrospective review |
| topic | palmoplantar psoriasis hand eczema atopic dermatitis biologic |
| url | http://dx.doi.org/10.1080/09546634.2019.1702147 |
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