Disulfiram inhibits neutrophil extracellular trap formation and protects rodents from acute lung injury and SARS-CoV-2 infection
Severe acute lung injury has few treatment options and a high mortality rate. Upon injury, neutrophils infiltrate the lungs and form neutrophil extracellular traps (NETs), damaging the lungs and driving an exacerbated immune response. Unfortunately, no drug preventing NET formation has completed cli...
| Main Authors: | , , , , , , , , , , , , |
|---|---|
| 格式: | 文件 |
| 语言: | English |
| 出版: |
American Society for Clinical investigation
2022-03-01
|
| 丛编: | JCI Insight |
| 主题: | |
| 在线阅读: | https://doi.org/10.1172/jci.insight.157342 |